Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7564651 | 0.83 | ALDH1A1 (0.51) | PRSS1KDM4EGAAMEN1KMT2A | |
| SCHEMBL4653935 | 0.83 | ALDH1A1 (0.49) | PRSS1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL2213228 | 0.82 | PRSS1 (0.56) | PRSS1KDM4EGAAKMT2AALDH1A1 | |
| SCHEMBL7567675 | 0.82 | ALDH1A1 (0.55) | PRSS1KDM4EGAAMEN1KMT2A | |
| SCHEMBL8164415 | 0.81 | NPC1 (0.70) | KDM4EMEN1KMT2AALDH1A1HTT | |
| SCHEMBL9320548 | 0.81 | NPC1 (0.70) | KDM4EMEN1KMT2AALDH1A1HTT | |
| SCHEMBL27837027 | 0.81 | CYSLTR2 (0.55) | PRSS1KDM4EGAAMEN1KMT2A | |
| SCHEMBL9699096 | 0.80 | THRA (0.60) | PRSS1GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL9697325 | 0.80 | THRA (0.60) | PRSS1GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL27634054 | 0.80 | S1PR4 (0.56) | PRSS1KDM4EGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11867698-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2024-01-09 | — | — | US | disclosed |
| US-20210041465-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2021-02-11 | — | — | US | disclosed |
| US-10845373-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2020-11-24 | — | — | US | disclosed |
| US-20180238912-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2018-08-23 | — | — | US | disclosed |
| US-9939454-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2018-04-10 | — | — | US | disclosed |
| US-9939454-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2018-04-10 | — | — | US | disclosed |
| US-9910051-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2018-03-06 | — | — | US | disclosed |
| US-9910051-B2 | Fluorogenic pH sensitive dyes and their method of use | Life Technologies Corporation (US) | 2018-03-06 | — | — | US | disclosed |
| US-20160139158-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2016-05-19 | — | — | US | disclosed |
| US-20160139158-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation | 2016-05-19 | — | — | US | disclosed |
| EP-2064290-B1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | LIFE TECHNOLOGIES CORP (US) | 2013-10-09 | — | — | EP | disclosed |
| US-20130102021-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2013-04-25 | — | — | US | disclosed |
| US-20130102021-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2013-04-25 | — | — | US | disclosed |
| US-20130102021-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2013-04-25 | — | — | US | disclosed |
| EP-2064290-A2 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2009-06-03 | — | — | EP | disclosed |
| US-20080274907-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | INVITROGEN CORPORATION (US) | 2008-11-06 | — | — | US | disclosed |
| US-20080274907-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | INVITROGEN CORPORATION (US) | 2008-11-06 | — | — | US | disclosed |
| US-20080274907-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | INVITROGEN CORPORATION (US) | 2008-11-06 | — | — | US | disclosed |
| WO-2008076524-A2 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2008-06-26 | — | — | WO | disclosed |
| WO-2008076524-A2 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | Life Technologies Corporation (US) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180238912-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | SLC11A2, MAN2B1, CD47 | PRSS1 1752/4885KDM4E 3702/4885GAA 27/4885 |
| US-20080274907-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | SLC11A2, MAN2B1, CD47 | PRSS1 1752/4885KDM4E 3702/4885GAA 27/4885 |
| US-10845373-B2 | Fluorogenic pH sensitive dyes and their method of use | SLC11A2, MAN2B1, CD47 | PRSS1 1752/4885KDM4E 3702/4885GAA 27/4885 |
| US-20210041465-A1 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE | SLC11A2, MAN2B1, CD47 | PRSS1 1752/4885KDM4E 3702/4885GAA 27/4885 |
| US-11867698-B2 | Fluorogenic pH sensitive dyes and their method of use | SLC11A2, MAN2B1, CD47 | PRSS1 1752/4885KDM4E 3702/4885GAA 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.