SCHEMBL4121058

SCHEMBL4121058

CCN1CCc2ccccc2[C@@H](N)C1=O

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PRCP P42785 2/20 0.46
ANPEP P15144 2/20 0.44
HTR2A P28223 2/20 0.41
XIAP P98170 1/20 0.40
TRPM8 Q7Z2W7 1/20 0.38
RET P07949 1/20 0.38
MEN1 O00255 1/20 0.38
USP2 O75604 1/20 0.38
ALDH1A1 P00352 1/20 0.38
CDK4 P11802 1/20 0.38
ALOX15 P16050 1/20 0.38
CCND1 P24385 1/20 0.38
KMT2A Q03164 1/20 0.38
HTR1A P08908 2/20 0.37
MTNR1B P49286 1/20 0.36
CHRNA7 P36544 1/20 0.36
OPRM1 P35372 1/20 0.36
OPRK1 P41145 1/20 0.36
OPRL1 P41146 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4116682 1.00 PRCP (0.46) PRCPANPEPHTR2AXIAPTRPM8
SCHEMBL4120258 1.00 PRCP (0.46) PRCPANPEPHTR2AXIAPTRPM8
SCHEMBL4117548 0.82 SIGMAR1 (0.48) ANPEP
SCHEMBL4128510 0.82 SIGMAR1 (0.48) ANPEP
SCHEMBL4117310 0.82 SIGMAR1 (0.48) ANPEP
SCHEMBL4552272 0.81 PRCP (0.49) PRCPANPEPHTR2ATRPM8ALDH1A1
SCHEMBL4969263 0.81 PRCP (0.49) PRCPANPEPHTR2ATRPM8ALDH1A1
SCHEMBL14169872 0.81 PRCP (0.44) PRCPXIAPMEN1USP2ALDH1A1
SCHEMBL4415387 0.80 SRD5A1 (0.40) MTNR1BOPRM1
SCHEMBL4415385 0.80 SRD5A1 (0.40) MTNR1BOPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8258302-B2 Method for producing benzazepinone API CORPORATION (JP) 2012-09-04 US disclosed
US-20090171090-A1 METHOD FOR PRODUCING BENZAZEPINONE API CORPORATION (JP) 2009-07-02 US disclosed
EP-1985615-A1 METHOD FOR PRODUCING BENZAZEPINONE API Corporation (JP) 2008-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090171090-A1 METHOD FOR PRODUCING BENZAZEPINONE NISCH, GABBR1, GABBR2 PRCP 1094/4885ANPEP 709/4885HTR2A 428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.