SCHEMBL4121484

SCHEMBL4121484

COc1cc(Cl)c(O)c(CC(C)C=O)c1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.36
ERN1 O75460 5/20 0.36
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
POLB P06746 2/20 0.33
MEN1 O00255 1/20 0.33
MCL1 Q07820 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ABL1 P00519 1/20 0.33
MAPT P10636 1/20 0.33
RECQL P46063 1/20 0.33
RIN1 Q13671 1/20 0.33
CTDSP1 Q9GZU7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4115276 0.83 ERN1 (0.31) ERN1
SCHEMBL4120606 0.81 ALOX15 (0.36) ERN1
SCHEMBL28173580 0.79 CA1 (0.37) KMT2APOLBMEN1KDM4EABL1
SCHEMBL21823051 0.78 ERN1 (0.37) KMT2AERN1POLBMEN1MCL1
SCHEMBL4121937 0.76 ERN1 (0.50) KMT2AERN1MEN1MCL1KDM4E
SCHEMBL4132597 0.73 CYP1A2 (0.39) KMT2AERN1MEN1KDM4EMAPT
SCHEMBL3639794 0.73 POLB (0.51) KMT2AERN1POLBKDM4E
SCHEMBL29025470 0.71 CYP3A4 (0.50) KMT2APOLBMEN1MCL1ABL1
SCHEMBL11557280 0.71 TP53 (0.44) KMT2AMEN1
SCHEMBL4376307 0.69 ERN1 (0.58) ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090221596-A1 Substtituted aryl oximes BAYER CROPSCIENCE AG (DE) 2009-09-03 US disclosed
EP-1883622-A1 SUBSTITUTED ARYL OXIMES Bayer CropScience Aktiengesellschaft (DE) 2008-02-06 EP disclosed
WO-2007090434-A1 SUBSTITUTED ARYL OXIMES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-08-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090221596-A1 Substtituted aryl oximes CYP1A1, PRDX1, CYP1A2 KMT2A 796/4885ERN1 961/4885MAOA 47/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.