SCHEMBL412170

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14619161	0.87	PTGS1 (0.46)	PTGS1PTGS2TUBB4ATUBBTUBA3C
	SCHEMBL412205	0.86	ALDH1A1 (0.48)	PTGS1PTGS2ALDH1A1SMN1; SMN2POLB
	SCHEMBL411779	0.86	PTGS1 (0.49)	PTGS1PTGS2TUBB4ATUBBTUBA3C
	SCHEMBL411520	0.85	TUBB4A (0.59)	PTGS1PTGS2TUBB4ATUBBTUBA3C
	SCHEMBL411397	0.85	ALDH1A1 (0.47)	PTGS1PTGS2ALDH1A1SMN1; SMN2POLB
	SCHEMBL410897	0.85	ALDH1A1 (0.47)	PTGS1PTGS2TUBB4ATUBBTUBA3C
	SCHEMBL408302	0.85	ALDH1A1 (0.47)	PTGS1PTGS2TUBB4ATUBBTUBA3C
	SCHEMBL407552	0.84	ALDH1A1 (0.54)	ALDH1A1SMN1; SMN2POLBMAPTMEN1
	SCHEMBL413385	0.83	ALDH1A1 (0.43)	ALDH1A1SMN1; SMN2POLB
	SCHEMBL413876	0.83	SMN1; SMN2 (0.45)	PTGS2TUBB1ALDH1A1SMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.