Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2747487 | 0.98 | GPR84 (0.52) | CFTRSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL31739381 | 0.98 | GPR84 (0.52) | CFTRSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL155191 | 0.81 | MEN1 (0.58) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL29567690 | 0.81 | MEN1 (0.58) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28624457 | 0.79 | MEN1 (0.56) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL28628671 | 0.79 | MEN1 (0.56) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| Water SCHEMBL27616945 | 0.79 | MEN1 (0.56) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| Methane SCHEMBL5065725 | 0.79 | MEN1 (0.56) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10550137 | 0.79 | MEN1 (0.56) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL27702719 | 0.79 | MEN1 (0.56) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064200-A1 | DERIVATIVES OF 2-PHENYL-3-HYDROXYQUINOLINE-4(1H)-ONE AND METHODS OF THEIR PREPARATION AND UTILIZATION | Univerzita Palackeho (CZ) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008028427-A1 | DERIVATIVES OF 2-PHENYL-3-HYDROXYQUINOLINE-4(1H)-ONE AND METHODS OF THEIR PREPARATION AND UTILIZATION | UNIVERZITA PALACKEHO (CZ) | 2008-03-13 | — | — | WO | disclosed |