Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CFTR | P13569 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31739381 | 1.00 | GPR84 (0.52) | GPR84ALDH1A1ATMMEN1MAPT | |
| Benzene SCHEMBL4121719 | 0.98 | CFTR (0.53) | GPR84ALDH1A1ATMMEN1MAPT | |
| SCHEMBL29567690 | 0.82 | MEN1 (0.58) | GPR84ALDH1A1ATMMEN1MAPT | |
| SCHEMBL155191 | 0.82 | MEN1 (0.58) | GPR84ALDH1A1ATMMEN1MAPT | |
| Hydrochloric Acid SCHEMBL28628671 | 0.80 | MEN1 (0.56) | GPR84ALDH1A1ATMMEN1MAPT | |
| SCHEMBL28624457 | 0.80 | MEN1 (0.56) | GPR84ALDH1A1ATMMEN1MAPT | |
| SCHEMBL10550137 | 0.80 | MEN1 (0.56) | GPR84ALDH1A1ATMMEN1MAPT | |
| Methane SCHEMBL5065725 | 0.80 | MEN1 (0.56) | GPR84ALDH1A1ATMMEN1MAPT | |
| SCHEMBL27702719 | 0.80 | MEN1 (0.56) | GPR84ALDH1A1ATMMEN1MAPT | |
| Water SCHEMBL27616945 | 0.80 | MEN1 (0.56) | GPR84ALDH1A1ATMMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866842-A2 | A COMPOSITION, METHOD OF AUTHENTICATING, METHODS OF MAKING AUTHENTICATABLE COMPOSITIONS, AUTHENTICATABLE ARTICLES MADE THERE FROM | General Electric Company (US) | 2007-12-19 | — | — | EP | claimed |
| WO-2006065561-A2 | A COMPOSITION, METHOD OF AUTHENTICATING, METHODS OF MAKING AUTHENTICATABLE COMPOSITIONS, AUTHENTICATABLE ARTICLES MADE THERE FROM | GENERAL ELECTRIC COMPANY (US) | 2006-06-22 | — | — | WO | claimed |
| US-20060131761-A1 | Composition, method of authenticating, methods of making authenticatable compositions, authenticatable articles made there from | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2006-06-22 | — | — | US | claimed |
| US-11753222-B2 | Powdered pouch and method of making same | MONOSOL, LLC (US) | 2023-09-12 | — | — | US | disclosed |
| EP-2825624-B2 | WATER SOLUBLE COMPOSITIONS INCORPORATING ENZYMES, AND METHOD OF MAKING SAME | MONOSOL LLC (US) | 2022-07-27 | — | — | EP | disclosed |
| EP-2838811-B2 | POWDERED POUCH AND METHOD OF MAKING SAME | MONOSOL LLC (US) | 2022-06-29 | — | — | EP | disclosed |
| EP-2763539-B1 | ANTIBACTERIAL COMPOUNDS | GLAXO GROUP LTD (GB) | 2017-02-08 | — | — | EP | disclosed |
| US-9340556-B2 | Antibacterial compounds | GLAXO GROUP LIMITED (GB) | 2016-05-17 | — | — | US | disclosed |
| CN-101972492-B | Medical product for curing body channel narrow and preventing dangerous restenosis | HEMOTEQ AG | 2014-12-10 | — | — | CN | disclosed |
| US-20140249126-A1 | ANTIBACTERIAL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2014-09-04 | — | — | US | disclosed |
| CN-101687066-B | Medical product for treating stenosis of body passageways and preventing dangerous restenosis | HEMOTEQ AG | 2013-09-11 | — | — | CN | disclosed |
| EP-1642109-A4 | METHODS FOR CONDUCTING ASSAYS FOR ENZYME ACTIVITY ON PROTEIN MICROARRAYS | PROTOMETRIX INC (US) | 2007-09-05 | — | — | EP | disclosed |
| US-20060131761-A1 | Composition, method of authenticating, methods of making authenticatable compositions, authenticatable articles made there from | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2006-06-22 | — | — | US | disclosed |
| WO-2006065561-A2 | A COMPOSITION, METHOD OF AUTHENTICATING, METHODS OF MAKING AUTHENTICATABLE COMPOSITIONS, AUTHENTICATABLE ARTICLES MADE THERE FROM | GENERAL ELECTRIC COMPANY (US) | 2006-06-22 | — | — | WO | disclosed |
| EP-1642109-A2 | METHODS FOR CONDUCTING ASSAYS FOR ENZYME ACTIVITY ON PROTEIN MICROARRAYS | Protometrix, Inc. (US) | 2006-04-05 | — | — | EP | disclosed |
| US-6919335-B2 | Administering a therapeutically effective amount of a heterocyclic compound to the patient for the treatment of inosine monophosphate dehydrogenase associated disorders, such as allograft rejection | BRISTOL-MYERS SQUIBB CO. (US) | 2005-07-19 | — | — | US | disclosed |
| WO-2005003721-A2 | ENZYME ACTIVITY ASSAYS ON PROTEIN MICROARRAYS | PROTOMETRIX, INC. (US) | 2005-01-13 | — | — | WO | disclosed |
| EP-1276739-A2 | HETEROCYCLES THAT ARE INHIBITORS OF IMPDH ENZYME | Bristol-Myers Squibb Company (US) | 2003-01-22 | — | — | EP | disclosed |
| US-20020040022-A1 | Heterocycles that are inhibitors of IMPDH enzyme | BRISTOL-MYERS SQUIBB COMPANY | 2002-04-04 | — | — | US | disclosed |
| WO-2001081340-A2 | HETEROCYCLES THAT ARE INHIBITORS OF IMPDH ENZYME | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020040022-A1 | Heterocycles that are inhibitors of IMPDH enzyme | XDH, IMPDH1, IMPDH2 | GPR84 3934/4885ALDH1A1 155/4885ATM 2467/4885 |
| US-20140249126-A1 | ANTIBACTERIAL COMPOUNDS | MRPL21, PEPD, ABCB11 | GPR84 4339/4885ALDH1A1 3841/4885ATM 3801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.