Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MELK | Q14680 | 5/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4122359 | 0.91 | CNR2 (0.44) | ALDH1A1TSHRNPSR1AKR1C2AKR1C1 | |
| SCHEMBL424526 | 0.85 | AKR1C4 (0.58) | ALDH1A1TSHRAKR1C2AKR1C1AKR1C4 | |
| SCHEMBL13696933 | 0.82 | AKR1C2 (0.41) | ALDH1A1TSHRNPSR1AKR1C2AKR1C1 | |
| SCHEMBL14435146 | 0.78 | ALDH1A1 (0.36) | ALDH1A1TSHRNPSR1MGLLCYP3A4 | |
| SCHEMBL4129952 | 0.78 | NPC1 (0.43) | ALDH1A1MGLLHPGDHSD17B10MELK | |
| SCHEMBL4125864 | 0.78 | TPMT (0.41) | ALDH1A1TSHRNPSR1MGLLCYP3A4 | |
| SCHEMBL13696934 | 0.75 | NPC1 (0.43) | TSHRNPSR1AKR1C2AKR1C1CYP2D6 | |
| SCHEMBL29394521 | 0.74 | AKR1C2 (0.69) | ALDH1A1TSHRAKR1C2AKR1C1AKR1C4 | |
| SCHEMBL4625424 | 0.74 | AKR1C2 (0.69) | ALDH1A1TSHRAKR1C2AKR1C1AKR1C4 | |
| SCHEMBL4127393 | 0.72 | AKR1C2 (0.45) | ALDH1A1TSHRAKR1C2AKR1C1AKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221596-A1 | Substtituted aryl oximes | BAYER CROPSCIENCE AG (DE) | 2009-09-03 | — | — | US | disclosed |
| US-20090221596-A1 | Substtituted aryl oximes | BAYER CROPSCIENCE AG (DE) | 2009-09-03 | — | — | US | disclosed |
| US-20090221596-A1 | Substtituted aryl oximes | BAYER CROPSCIENCE AG (DE) | 2009-09-03 | — | — | US | disclosed |
| CN-101193855-A | Substituted aryl oximes | BAYER CROPSCIENCE AG (DE) | 2008-06-04 | — | — | CN | disclosed |
| EP-1883622-A1 | SUBSTITUTED ARYL OXIMES | Bayer CropScience Aktiengesellschaft (DE) | 2008-02-06 | — | — | EP | disclosed |
| WO-2007090434-A1 | SUBSTITUTED ARYL OXIMES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221596-A1 | Substtituted aryl oximes | CYP1A1, PRDX1, CYP1A2 | ALDH1A1 319/4885TSHR 285/4885NPSR1 660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.