Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 7/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MELK | Q14680 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435149 | 0.93 | CNR2 (0.40) | TSHRMGLLDRD2MELKLMNA | |
| SCHEMBL4121777 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TSHRNPSR1MGLLTYK2 | |
| SCHEMBL4125864 | 0.75 | TPMT (0.41) | ALDH1A1TSHRNPSR1MGLLDRD2 | |
| SCHEMBL10937568 | 0.73 | CYP3A4 (0.50) | ALDH1A1TSHRCYP3A4MEN1PTGS1 | |
| SCHEMBL4122359 | 0.71 | CNR2 (0.44) | ALDH1A1TSHRNPSR1MGLLMEN1 | |
| SCHEMBL4132557 | 0.69 | TAS1R3 (0.41) | ALDH1A1TSHRDRD2DRD3KMT2A | |
| SCHEMBL27712795 | 0.66 | HSP90AB1 (0.47) | CYP3A4MEN1PTGS1DRD3KMT2A | |
| SCHEMBL13696933 | 0.66 | AKR1C2 (0.41) | ALDH1A1TSHRNPSR1CYP3A4MEN1 | |
| SCHEMBL12303010 | 0.65 | AKR1C4 (0.40) | ALDH1A1TSHRCYP3A4MEN1KMT2A | |
| SCHEMBL424526 | 0.65 | AKR1C4 (0.58) | ALDH1A1TSHRCYP3A4MEN1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007090434-A1 | SUBSTITUTED ARYL OXIMES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-08-16 | — | — | WO | disclosed |