Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | NPY4R | P50391 | 10/20 | 0.44 |
| ▸ | NPY1R | P25929 | 5/20 | 0.44 |
| ▸ | NPY2R | P49146 | 4/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13050780 | 0.86 | NOD1 (0.48) | KMT2ANPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL463466 | 0.86 | NPY4R (0.52) | KMT2APOLBNPY4RNPY1RNPY2R | |
| SCHEMBL7904153 | 0.84 | L3MBTL1 (0.67) | KMT2APOLBL3MBTL1NOD1KDM4E | |
| SCHEMBL3935159 | 0.83 | NPY4R (0.44) | NPY4RNPY1RNPY2RNPY5RNOD1 | |
| SCHEMBL411635 | 0.82 | KMT2A (0.58) | KMT2APOLBL3MBTL1NOD1KDM4E | |
| SCHEMBL30434218 | 0.81 | NPY4R (0.59) | NPY4RNPY1RNPY2RNPY5RNOD1 | |
| SCHEMBL18049032 | 0.81 | NPY4R (0.43) | NPY4RNPY1RNPY2RNPY5RNOD1 | |
| Hydrochloric Acid SCHEMBL15512550 | 0.81 | NPY4R (0.45) | NPY4RNPY1RNPY2RNPY5RDPP7 | |
| SCHEMBL23836846 | 0.80 | NPY4R (0.42) | KMT2APOLBL3MBTL1NPY4RNPY1R | |
| Hydrochloric Acid SCHEMBL30380134 | 0.80 | NPY4R (0.58) | NPY4RNPY1RNPY2RNPY5RNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8871252-B2 | pH-responsive liposome | NANOTHETA CO, LTD. (JP) | 2014-10-28 | — | — | US | disclosed |
| US-20120064148-A1 | PH-RESPONSIVE LIPOSOME | BIONANOSHEETER CO., LTD. (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120064148-A1 | PH-RESPONSIVE LIPOSOME | LIPA, SMPD3, SMPD1 | KMT2A 2691/4885POLB 4763/4885L3MBTL1 1139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.