SCHEMBL23836846

SCHEMBL23836846

CCOC(=O)C(CCCNC(=N)N)NC(=O)C(C)C

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 13/20 0.42
▸ NPY1R P25929 9/20 0.42
▸ KMT2A Q03164 2/20 0.40
▸ POLB P06746 1/20 0.40
▸ NPY5R Q15761 8/20 0.39
▸ NPY2R P49146 5/20 0.39
▸ CAD P27708 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17015152 0.89 NPY4R (0.50) NPY4RNPY1RNPY5RNPY2R
SCHEMBL21879811 0.87 KMT2A (0.42) NPY4RNPY1RKMT2APOLBNPY5R
SCHEMBL5812127 0.86 SIRT6 (0.43) NPY4RNPY1RKMT2APOLBNPY5R
SCHEMBL5812133 0.86 SIRT6 (0.43) NPY4RNPY1RKMT2APOLBNPY5R
SCHEMBL26017775 0.85 KMT2A (0.47) NPY4RNPY1RKMT2APOLBNPY5R
SCHEMBL5366976 0.84 SIRT6 (0.43) NPY4RNPY1RKMT2APOLBNPY5R
SCHEMBL4599236 0.83 CAD (0.39) NPY4RNPY1RKMT2APOLBNPY5R
SCHEMBL27554606 0.83 CAD (0.39) NPY4RNPY1RKMT2APOLBNPY5R
SCHEMBL27481242 0.83 CAD (0.39) NPY4RNPY1RKMT2APOLBNPY5R
SCHEMBL8019370 0.83 CAD (0.39) NPY4RNPY1RKMT2APOLBNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11123304-B2 Nanoparticles having poly(ester amide) polymer cores as drug delivery vehicles THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2021-09-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11123304-B2 Nanoparticles having poly(ester amide) polymer cores as drug delivery vehicles ASGR1, F12, MSR1 NPY4R 294/4885NPY1R 76/4885KMT2A 3342/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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