SCHEMBL412228

SCHEMBL412228

Fc1ccc(-c2ccccc2)c(F)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.49
PTGS1 P23219 3/20 0.49
KMT2A Q03164 3/20 0.49
PTGS2 P35354 2/20 0.49
SLC22A6 Q4U2R8 2/20 0.49
LMNA P02545 2/20 0.49
HPGD P15428 2/20 0.49
HIF1A Q16665 2/20 0.49
MAPT P10636 2/20 0.49
TTR P02766 2/20 0.49
FABP2 P12104 1/20 0.49
TSHR P16473 1/20 0.49
AKR1C4 P17516 1/20 0.49
ADRA2B P18089 1/20 0.49
CHRM3 P20309 1/20 0.49
HTR2C P28335 1/20 0.49
DRD3 P35462 1/20 0.49
AKR1C3 P42330 1/20 0.49
AKR1C2 P52895 1/20 0.49
AKR1C1 Q04828 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30216000 1.00 MEN1 (0.49) MEN1PTGS1KMT2APTGS2SLC22A6
SCHEMBL18561607 0.96 MEN1 (0.50) MEN1PTGS1KMT2APTGS2SLC22A6
Ethylene SCHEMBL27852304 0.96 MEN1 (0.46) MEN1PTGS1KMT2APTGS2SLC22A6
SCHEMBL18430879 0.94 MEN1 (0.53) MEN1PTGS1KMT2APTGS2SLC22A6
Chloromethane SCHEMBL27622109 0.94 MEN1 (0.49) MEN1PTGS1KMT2APTGS2SLC22A6
SCHEMBL16673243 0.94 MEN1 (0.49) MEN1PTGS1KMT2APTGS2SLC22A6
Sulfur Dioxide SCHEMBL28061237 0.92 MEN1 (0.47) MEN1PTGS1KMT2APTGS2SLC22A6
SCHEMBL2238426 0.88 PTGES2 (0.46) MEN1PTGS1KMT2APTGS2SLC22A6
SCHEMBL9057929 0.85 ALDH1A1 (0.52) MEN1PTGS1KMT2APTGS2SLC22A6
SCHEMBL18716177 0.85 CYP2C9 (0.47) MEN1PTGS1KMT2APTGS2SLC22A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240339730-A1 ELECTROCHEMICAL DEVICE NINGDE AMPEREX TECHNOLOGY LIMITED (CN) 2024-10-10 US claimed
EP-4411963-A2 ELECTROCHEMICAL DEVICE Ningde Amperex Technology Ltd. (CN) 2024-08-07 EP claimed
US-12057602-B2 Electrochemical device NINGDE AMPEREX TECHNOLOGY LIMITED (CN) 2024-08-06 US claimed
EP-3966880-B1 ELECTROCHEMICAL DEVICE NINGDE AMPEREX TECHNOLOGY LTD (CN) 2024-07-31 EP claimed
CN-117976982-A Sodium ion battery electrolyte, preparation method thereof and sodium ion battery 桂林电子科技大学 2024-05-03 CN claimed
CN-117954685-A Flame-retardant electrolyte and lithium ion battery using same 中国石油化工股份有限公司 2024-04-30 CN claimed
CN-114605289-B Carbamate compound for nonaqueous electrolyte and application thereof 湖州师范学院 2023-11-17 CN claimed
CN-112010894-B Phosphorothioate compound, nonaqueous lithium ion battery electrolyte containing phosphorothioate compound and lithium ion battery 湖州师范学院 2023-08-11 CN claimed
US-20230198096-A1 ELECTROCHEMICAL DEVICE NINGDE AMPEREX TECHNOLOGY LIMITED (CN) 2023-06-22 US claimed
US-11637319-B2 Electrolytic solution and electrochemical device NINGDE AMPEREX TECHNOLOGY LIMITED (CN) 2023-04-25 US claimed
CN-110408411-A Liquid-crystal composition and application thereof and liquid crystal display element JNC CORP 2019-11-05 CN claimed
US-7304065-B2 Melanin concentrating hormone antagonists THE PROCTER & GAMBLE COMPANY (US) 2007-12-04 US claimed
US-20050075324-A1 Melanin concentrating hormone antagonists THE PROCTER & GAMBLE COMPANY (US) 2005-04-07 US claimed
US-5142093-A Process for the preparation of 4-(2,4-difluorophenyl)-phenyl 4-nitro-benzoate ZAMBON GROUP S.P.A. (IT) 1992-08-25 US claimed
EP-0180290-B1 OMEGA-(2',4'-DIHALOBIPHENYLYL)OXO ALKANOIC ACIDS AND PROCESS FOR THEIR PREPARATION SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu (CS) 1987-10-28 EP claimed
EP-0126287-B1 FLUORINATED COMPOUNDS HAVING ANALGESIC AND ANTIINFLAMMATORY ACTIVITIES MEDEA RESEARCH S.r.l. (IT) 1987-06-16 EP claimed
EP-0180290-A1 Omega-(2',4'-dihalobiphenylyl)oxo alkanoic acids and process for their preparation SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu (CS) 1986-05-07 EP claimed
EP-0126287-A1 Fluorinated compounds having analgesic and antiinflammatory activities MEDEA RESEARCH S.r.l. (IT) 1984-11-28 EP claimed
US-4225730-A Process for preparing 4-(2,4-difluorophenyl)-salicyclic acid MERCK & CO., INC. (US) 1980-09-30 US claimed
US-3992459-A BIARYL COUPLING BY DIAZOTIZATION MERCK & CO., INC. (US) 1976-11-16 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050075324-A1 Melanin concentrating hormone antagonists MCHR1, MCHR2, MC1R MEN1 238/4885PTGS1 2265/4885KMT2A 2516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.