SCHEMBL16673243

SCHEMBL16673243

Fc1ccc(-c2ccc(F)cc2)cc1.Fc1ccc(-c2ccccc2)c(F)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
LMNA P02545 2/20 0.49
HPGD P15428 2/20 0.49
HIF1A Q16665 2/20 0.49
SLC22A6 Q4U2R8 2/20 0.49
KDM4E B2RXH2 1/20 0.49
USP2 O75604 1/20 0.49
ALDH1A1 P00352 1/20 0.49
DHFR P00374 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
TTR P02766 1/20 0.49
ALB P02768 1/20 0.49
HMGB1 P09429 1/20 0.49
CXCL12 P48061 1/20 0.49
ACMSD Q8TDX5 1/20 0.49
HSD17B10 Q99714 1/20 0.49
GRM2 Q14416 1/20 0.46
TDP2 O95551 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18561607 0.98 MEN1 (0.50) MEN1KMT2ALMNAHPGDHIF1A
SCHEMBL412228 0.94 MEN1 (0.49) MEN1KMT2ALMNAHPGDHIF1A
SCHEMBL30216000 0.94 MEN1 (0.49) MEN1KMT2ALMNAHPGDHIF1A
SCHEMBL18430879 0.92 MEN1 (0.53) MEN1KMT2ALMNAHPGDHIF1A
SCHEMBL18716177 0.92 CYP2C9 (0.47) MEN1KMT2ALMNAHPGDHIF1A
Ethylene SCHEMBL27852304 0.89 MEN1 (0.46) MEN1KMT2ALMNAHPGDHIF1A
SCHEMBL9057929 0.89 ALDH1A1 (0.52) MEN1KMT2ALMNAHPGDHIF1A
Chloromethane SCHEMBL27622109 0.88 MEN1 (0.49) MEN1KMT2ALMNAHPGDHIF1A
Sulfur Dioxide SCHEMBL28061237 0.86 MEN1 (0.47) MEN1KMT2ALMNAHPGDHIF1A
SCHEMBL2140807 0.85 PTGS1 (0.49) MEN1KMT2ALMNAHPGDHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10320030-B2 Nonaqueous electrolyte solution and nonaqueous electrolyte battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2019-06-11 US disclosed
US-20150140448-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2015-05-21 US disclosed
EP-2869389-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTIC SOLUTION CELL USING SAME Mitsubishi Chemical Corporation (JP) 2015-05-06 EP disclosed
US-20140107135-A1 PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 AUSPEX PHARMACEUTICALS, INC. (US) 2014-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140107135-A1 PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 PLA2G1B, PLA2G4A, PLA2G4B MEN1 3297/4885KMT2A 1547/4885LMNA 622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.