SCHEMBL4122283

SCHEMBL4122283

CC(O)C(=O)OC(=O)C(C)(O)C(=O)CO

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7618998 0.93
SCHEMBL4108757 0.79
SCHEMBL190574 0.76 MAPT (0.43)
SCHEMBL190077 0.76 MAPT (0.43)
SCHEMBL27468130 0.76 TP53 (0.33)
SCHEMBL1668708 0.75 PRKCA (0.36) PRKCA
SCHEMBL27894227 0.75 PRKCA (0.32) PRKCA
SCHEMBL11433341 0.73 PRKCA (0.36) PRKCA
SCHEMBL27449363 0.73 MMP8 (0.33)
SCHEMBL1591709 0.69 TDP1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090105196-A1 USE OF CREATINE COMPOUNDS TO TREAT DERMATITIS AVICENA GROUP, INC. 2009-04-23 US disclosed
WO-2009002913-A1 USE OF CREATINE COMPOUNDS TO TREAT DERMATITIS AVICENA GROUP, INC. (US) 2008-12-31 WO disclosed
EP-1207846-B1 TOWELETTE PRODUCT UNILEVER PLC (GB) 2006-10-18 EP disclosed
EP-1161518-B1 TOWELETTE PRODUCT UNILEVER PLC (GB) 2006-05-31 EP disclosed
CN-1182835-C Towelette product 2005-01-05 CN disclosed
US-6767924-B2 COMPRISES 2-KETOETHANOIC ACID FOR COSMETIC CONDITIONS AND DERMATOLOGIC DISORDERS TRISTRATA TECHNOLOGY, INC. 2004-07-27 US disclosed
US-20030083380-A1 Method of using hydroxycarboxylic acids or related compounds for treating skin changes asociated with intrinsic and extrinsic aging YU RUEY J (US) 2003-05-01 US disclosed
US-20030044362-A1 Method and product for skin lightening UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-03-06 US disclosed
US-20030017130-A1 Additives enhancing topical applications of therapeutic agents TRISTRATA, INC. 2003-01-23 US disclosed
CN-1378442-A Towlette product UNILEVER NV (NL) 2002-11-06 CN disclosed
US-5643961-A TREATMENT OF SKIN WITH COSMETICS TRISTRATA TECHNOLOGY, INC. (US) 1997-07-01 US disclosed
US-5643952-A SKIN DISORDERS TRISTRATA TECHNOLOGY, INC. (US) 1997-07-01 US disclosed
US-5643963-A AGING RESISTANCE OF SKIN BY REDUCING WRINKLES TRISTRATA TECHNOLOGY, INC. (US) 1997-07-01 US disclosed
US-5643962-A SKIN DISORDERS TRISTRATA TECHNOLOGY, INC. (US) 1997-07-01 US disclosed
US-5637615-A ANTIAGING AGENT TRISTRATA TECHNOLOGY, INC. (US) 1997-06-10 US disclosed
EP-0413528-B1 Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use YU RUEY J (US) 1995-11-15 EP disclosed
EP-0671162-A2 Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use Yu, Ruey J., Dr. (US) 1995-09-13 EP disclosed
US-5385938-A application of mixtures containing hydroxyacetic acid(or its salts) to skin IGI, INC. 1995-01-31 US disclosed
US-5091171-A Skin disorders IGI, INC. 1992-02-25 US disclosed
EP-0413528-A1 Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use Yu, Ruey J., Dr. (US) 1991-02-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090105196-A1 USE OF CREATINE COMPOUNDS TO TREAT DERMATITIS CKMT1A; CKMT1B, CRAT, LRAT PRKCA 271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.