⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7618998 | 0.88 | — | — | |
| SCHEMBL4122283 | 0.79 | PRKCA (0.30) | — | |
| SCHEMBL17964190 | 0.78 | DGAT1 (0.37) | — | |
| SCHEMBL11433341 | 0.78 | PRKCA (0.36) | — | |
| SCHEMBL1404108 | 0.78 | MMP8 (0.43) | — | |
| SCHEMBL2505759 | 0.76 | MAPK1 (0.39) | — | |
| SCHEMBL1403998 | 0.75 | ALDH1A1 (0.32) | — | |
| SCHEMBL31019978 | 0.72 | MAPT (0.45) | — | |
| SCHEMBL4104339 | 0.72 | — | — | |
| SCHEMBL29868055 | 0.72 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006084174-A2 | IMPROVED BIOAVAILABILITY AND IMPROVED DELIVERY OF ALKALINE PHARMACEUTICAL DRUGS | YU RUEY J (US) | 2006-08-10 | — | — | WO | claimed |
| EP-1601366-A1 | IMPROVED BIOAVAILABILITY AND IMPROVED DELIVERY OF ALKALINE PHARMACEUTICAL DRUGS | Yu, Ruey J., Dr. (US) | 2005-12-07 | — | — | EP | claimed |
| US-20050196418-A1 | Bioavailability and improved delivery of alkaline pharmaceutical drugs | YU RUEY J (US) | 2005-09-08 | — | — | US | claimed |
| US-20040214215-A1 | Bioavailability and improved delivery of alkaline pharmaceutical drugs | YU RUEY J (US) | 2004-10-28 | — | — | US | claimed |
| WO-2004080468-A1 | IMPROVED BIOAVAILABILITY AND IMPROVED DELIVERY OF ALKALINE PHARMACEUTICAL DRUGS | YU RUEY J (US) | 2004-09-23 | — | — | WO | claimed |
| EP-1009398-A4 | MOLECULAR COMPLEX AND CONTROL-RELEASE OF ALPHA HYDROXYACIDS | YU RUEY J (US) | 2004-06-23 | — | — | EP | claimed |
| EP-1009398-A1 | MOLECULAR COMPLEX AND CONTROL-RELEASE OF ALPHA HYDROXYACIDS | Yu, Ruey J., Dr. (US) | 2000-06-21 | — | — | EP | claimed |
| US-5877212-A | HYDROGEN BONDING WITH COMPLEXING AGENT | YU RUEY J (US) | 1999-03-02 | — | — | US | claimed |
| WO-1998046217-A1 | MOLECULAR COMPLEX AND CONTROL-RELEASE OF ALPHA HYDROXYACIDS | YU RUEY J (US) | 1998-10-22 | — | — | WO | claimed |
| CN-102796071-B | The method being manufactured lactide by lactic acid | 现代自动车株式会社 | 2016-09-07 | — | — | CN | disclosed |
| CN-103830216-B | Lactic acid oligomer is used for treating the application in gynopathic medicine in preparation | 莱克瑞股份公司 | 2016-08-17 | — | — | CN | disclosed |
| US-20090105196-A1 | USE OF CREATINE COMPOUNDS TO TREAT DERMATITIS | AVICENA GROUP, INC. | 2009-04-23 | — | — | US | disclosed |
| WO-2009002913-A1 | USE OF CREATINE COMPOUNDS TO TREAT DERMATITIS | AVICENA GROUP, INC. (US) | 2008-12-31 | — | — | WO | disclosed |
| US-20080032937-A1 | Bioavailability and Improved Delivery of Alkaline Pharmaceutical Drugs | YU RUEY J | 2008-02-07 | — | — | US | disclosed |
| US-5637615-A | ANTIAGING AGENT | TRISTRATA TECHNOLOGY, INC. (US) | 1997-06-10 | — | — | US | disclosed |
| EP-0413528-B1 | Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use | YU RUEY J (US) | 1995-11-15 | — | — | EP | disclosed |
| EP-0671162-A2 | Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use | Yu, Ruey J., Dr. (US) | 1995-09-13 | — | — | EP | disclosed |
| US-5385938-A | application of mixtures containing hydroxyacetic acid(or its salts) to skin | IGI, INC. | 1995-01-31 | — | — | US | disclosed |
| US-5091171-A | Skin disorders | IGI, INC. | 1992-02-25 | — | — | US | disclosed |
| EP-0413528-A1 | Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use | Yu, Ruey J., Dr. (US) | 1991-02-20 | — | — | EP | disclosed |