Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL4121737 | 0.91 | GPR119 (0.39) | ACHEHTR2AHTR2CSLC6A4 | |
| SCHEMBL4114849 | 0.88 | ACHE (0.40) | ACHEBCHEHTR2AHTR2CSLC6A4 | |
| Dimethylamine SCHEMBL4114208 | 0.88 | ACHE (0.49) | ACHEBCHE | |
| SCHEMBL4122375 | 0.88 | ACHE (0.40) | ACHEBCHEHTR2AHTR2CSLC6A4 | |
| Dimethylamine SCHEMBL4120582 | 0.88 | ACHE (0.56) | ACHEBCHE | |
| Dimethylamine SCHEMBL4131906 | 0.87 | ACHE (0.55) | ACHEBCHE | |
| Dimethylamine SCHEMBL4112450 | 0.87 | ACHE (0.42) | ACHEBCHEALDH1A1MAOB | |
| Dimethylamine SCHEMBL4120903 | 0.86 | ACHE (0.41) | ACHEBCHEHTR2AHTR2CSLC6A4 | |
| Fumaric Acid SCHEMBL4130600 | 0.86 | ACHE (0.42) | ACHEBCHEHTR2AHTR2CSLC6A4 | |
| Dimethylamine SCHEMBL4126764 | 0.86 | ACHE (0.46) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
| EP-2017275-A1 | BENZISOXAZOLE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2009-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | NR1I2, NR1I3, NR0B1 | ACHE 3716/4885BCHE 2215/4885HTR2A 1251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.