SCHEMBL4122438

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4129872	0.93	ACHE (0.41)	ACHEPDCD1CD274MGLLCETP
	SCHEMBL4120919	0.91	GPR119 (0.44)	ACHECETPYAP1IRAK4GPR119
	SCHEMBL4133717	0.91	ACHE (0.47)	ACHEPDCD1CD274MGLL
	Dimethylamine SCHEMBL4129875	0.90	PDCD1 (0.42)	ACHEPDCD1CD274MGLLCETP
	SCHEMBL13596402	0.89	ACHE (0.46)	ACHEYAP1CSF1RKDR
	SCHEMBL4127679	0.86	GPR119 (0.39)	ACHECETPIRAK4GPR119FAAH
	SCHEMBL4113027	0.86	GPR119 (0.38)	ACHECETPGPR119CSF1RFAAH
	SCHEMBL4121012	0.86	GPR119 (0.39)	ACHEGPR119CSF1RFAAHKDR
	SCHEMBL4113058	0.85	EPHA2 (0.41)	ACHEYAP1GPR119CSF1RFAAH
	SCHEMBL4121129	0.85	CETP (0.41)	ACHEMGLLCETPNOTCH1GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.