Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 19/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL413710 | 0.89 | TGFBR1 (0.49) | NAMPTALDH1A1 | |
| SCHEMBL414211 | 0.88 | TGFBR1 (0.53) | ALDH1A1 | |
| SCHEMBL412491 | 0.88 | TGFBR1 (0.57) | ALDH1A1 | |
| SCHEMBL414681 | 0.88 | TGFBR1 (0.51) | ALDH1A1 | |
| SCHEMBL412977 | 0.88 | TGFBR1 (0.51) | NAMPT | |
| SCHEMBL409683 | 0.86 | TGFBR1 (0.48) | — | |
| SCHEMBL414592 | 0.86 | TGFBR1 (0.47) | NAMPTALDH1A1 | |
| SCHEMBL412319 | 0.86 | TGFBR1 (0.61) | — | |
| SCHEMBL413597 | 0.84 | TGFBR1 (0.48) | — | |
| SCHEMBL412989 | 0.84 | TGFBR1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120021519-A1 | EFFICIENT INDUCTION OF PLURIPOTENT STEM CELLS USING SMALL MOLECULE COMPOUNDS | PRESIDENTS AND FELLOWS OF HARVARD COLLEGE (US) | 2012-01-26 | — | — | US | disclosed |