Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | CARM1 | Q86X55 | 4/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 4/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 8/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4131722 | 0.86 | CARM1 (0.48) | OPRM1OPRL1CARM1PRMT6CHRM2 | |
| SCHEMBL5167763 | 0.79 | OPRM1 (0.54) | OPRM1OPRL1OPRK1 | |
| SCHEMBL14028057 | 0.77 | OPRM1 (0.58) | OPRM1OPRL1OPRK1 | |
| SCHEMBL4118199 | 0.77 | OPRL1 (0.55) | OPRM1OPRL1OPRK1 | |
| SCHEMBL4112325 | 0.76 | CARM1 (0.46) | CARM1PRMT6CHRM2CHRM1CHRM3 | |
| SCHEMBL14601364 | 0.76 | OPRM1 (0.76) | OPRM1OPRL1OPRK1TAAR1 | |
| Hydrochloric Acid SCHEMBL2877571 | 0.75 | OPRL1 (0.56) | OPRM1OPRL1OPRK1 | |
| SCHEMBL5382510 | 0.75 | OPRL1 (0.57) | OPRM1OPRL1OPRK1CHRM2CHRM1 | |
| SCHEMBL205961 | 0.75 | OPRL1 (0.57) | OPRM1OPRL1OPRK1 | |
| SCHEMBL5166242 | 0.74 | OPRM1 (0.51) | OPRM1OPRL1OPRK1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | SULT2A1, STS, SULT1A1 | OPRM1 2798/4885OPRL1 2189/4885OPRK1 2548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.