SCHEMBL4124849

SCHEMBL4124849

C=CCC1(CC=C)CC(=O)CC(C)(C)N1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.35
MMP9 P14780 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6130820 0.86 MMP9 (0.31) MMP9
Hydrochloric Acid SCHEMBL11365594 0.84 MMP9 (0.30) MMP9
SCHEMBL1803803 0.78 KDM4E (0.40) SMN1; SMN2
SCHEMBL1802898 0.74 SMN1; SMN2 (0.36) SMN1; SMN2
Ethylene SCHEMBL6311271 0.74 SMN1; SMN2 (0.52) SMN1; SMN2
SCHEMBL10902746 0.74 MMP9 (0.33) SMN1; SMN2MMP9
SCHEMBL38953 0.73 SMN1; SMN2 (0.56) SMN1; SMN2
SCHEMBL1802875 0.72 HSD17B10 (0.42) SMN1; SMN2
Water SCHEMBL7733637 0.71 SMN1; SMN2 (0.54) SMN1; SMN2
Hydrochloric Acid SCHEMBL20704047 0.71 SMN1; SMN2 (0.54) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1115765-B1 GRAFTING OF ETHYLENICALLY UNSATURATED MONOMERS ONTO POLYMERS CIBA HOLDING INC (CH) 2009-06-24 EP disclosed
WO-2009065774-A1 GRAFTING OF ETHYLENICALLY UNSATURATED MONOMERS ONTO POLYMERS IN SUPERCRITICAL CARBON DIOXIDE BASF SE (CH) 2009-05-28 WO disclosed
US-7402639-B2 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators CIBA SPECIALTY CHEMICALS CORP. (US) 2008-07-22 US disclosed
EP-1115766-B1 GRAFTING OF ETHYLENICALLY UNSATURATED MONOMERS ONTO POLYMERS CIBA SC HOLDING AG (CH) 2005-10-19 EP disclosed
US-6927295-B2 A polymerization catalyst for free radical polymerization of ethylenically unsaturated monomers CIBA SPECIALTY CHEMICALS CORP. (US) 2005-08-09 US disclosed
US-20050131177-A1 1-Alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators KRAMER ANDREAS (SE) 2005-06-16 US disclosed
US-6875831-B1 Mono and multifunctional alkoxyamines for the preparation of functionalized macromers CIBA SPECIALTY CHEMICALS CORP. (US) 2005-04-05 US disclosed
EP-1189875-B1 MONO AND MULTIFUNCTIONAL ALKOXYAMINES FOR THE PREPARATION OF FUNCTIONALIZED MACROMERS CIBA SC HOLDING AG (CH) 2004-08-04 EP disclosed
US-6683142-B2 PROVIDE POLYMERIC RESIN PRODUCTS HAVING LOW POLYDISPERSITY. CIBA SPECIALTY CHEMICALS CORPORATION 2004-01-27 US disclosed
US-20030220423-A1 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators KRAMER ANDREAS (CH) 2003-11-27 US disclosed
US-6525151-B1 Attaching stable nitroxyl radical to increase activity toward chemical modification and copolymerizing; adhesives; polymer blend compatibilizers or toughening agents CIBA SPECIALTY CHEMICALS CORPORATION 2003-02-25 US disclosed
US-6521710-B1 Grafting of ethylenically unsaturated monomers onto polymers CIBA SPECIALTY CHEMICALS CORPORATION 2003-02-18 US disclosed
US-20020107397-A1 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators KRAMER ANDREAS (CH) 2002-08-08 US disclosed
EP-1189875-A2 MONO AND MULTIFUNCTIONAL ALKOXYAMINES FOR THE PREPARATION OF FUNCTIONALIZED MACROMERS Ciba SC Holding AG (CH) 2002-03-27 EP disclosed
US-6353107-B1 FREE RADICAL CATALYSTS FOR ADDITION POLYMERIZATION; NARROW MOLECULAR WEIGHT DISTRIBUTION; HIGH PURITY AND COLORLESS CIBA SPECIALTY CHEMICALS CORPORATION 2002-03-05 US disclosed
EP-1115765-A1 GRAFTING OF ETHYLENICALLY UNSATURATED MONOMERS ONTO POLYMERS Ciba SC Holding AG (CH) 2001-07-18 EP disclosed
EP-1115766-A1 GRAFTING OF ETHYLENICALLY UNSATURATED MONOMERS ONTO POLYMERS Ciba SC Holding AG (CH) 2001-07-18 EP disclosed
WO-2001002345-A2 MONO AND MULTIFUNCTIONAL ALKOXYAMINES FOR THE PREPARATION OF FUNCTIONALIZED MACROMERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-01-11 WO disclosed
WO-2000014134-A1 GRAFTING OF ETHYLENICALLY UNSATURATED MONOMERS ONTO POLYMERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-03-16 WO disclosed
WO-2000014135-A1 GRAFTING OF ETHYLENICALLY UNSATURATED MONOMERS ONTO POLYMERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-03-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050131177-A1 1-Alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators PYM1, PTGER1, CBR1 SMN1; SMN2 2642/4885MMP9 3385/4885
US-20020107397-A1 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators CBR1, PYM1, ELOC SMN1; SMN2 2540/4885MMP9 3898/4885
US-20030220423-A1 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators PYM1, ELOC, CBR1 SMN1; SMN2 2580/4885MMP9 3920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.