Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 6/20 | 0.40 |
| ▸ | CNR2 | P34972 | 6/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4256479 | 0.78 | CHRNB2 (0.37) | SLC6A3KCNH2TAAR1 | |
| SCHEMBL295269 | 0.76 | CNR2 (0.46) | GSK3BCNR2CYP1A2CYP2D6 | |
| SCHEMBL20549681 | 0.76 | CNR2 (0.34) | CNR2 | |
| SCHEMBL1633511 | 0.76 | DRD3 (0.36) | CNR2 | |
| SCHEMBL3120324 | 0.76 | NPC1 (0.36) | CNR2SLC6A3 | |
| SCHEMBL5348965 | 0.72 | SLC2A1 (0.45) | — | |
| SCHEMBL16344786 | 0.71 | PTGS2 (0.49) | CNR2 | |
| SCHEMBL17004633 | 0.69 | KCNH2 (0.53) | CNR2KCNH2PDE10A | |
| SCHEMBL1744043 | 0.69 | HDAC4 (0.39) | — | |
| SCHEMBL16136726 | 0.69 | MEN1 (0.40) | GSK3BCNR2CYP1A2CYP2D6PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805142-A4 | NOVEL PYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | REDDY US THERAPEUTICS INC (US) | 2009-06-10 | — | — | EP | disclosed |
| EP-1805142-A2 | NOVEL PYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | Reddy US Therapeutics, Inc. (US) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006034474-A2 | NOVEL PYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | REDDY US THERAPEUTICS, INC. (US) | 2006-03-30 | — | — | WO | disclosed |