Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CCR2 | P41597 | 1/20 | 0.54 |
| ▸ | NOD2 | Q9HC29 | 4/20 | 0.54 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.54 |
| ▸ | BCL2 | P10415 | 1/20 | 0.48 |
| ▸ | BID | P55957 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4118405 | 0.87 | NOD2 (0.56) | ALDH1A1LMNAMAPTCCR2NOD2 | |
| SCHEMBL6864420 | 0.84 | ALDH1A1 (0.73) | ALDH1A1LMNAMAPTCCR2NOD2 | |
| SCHEMBL4121234 | 0.84 | CCR2 (0.72) | ALDH1A1LMNAMAPTCCR2NOD2 | |
| SCHEMBL31599460 | 0.84 | CCR2 (0.72) | ALDH1A1LMNAMAPTCCR2NOD2 | |
| SCHEMBL11927321 | 0.84 | NOD2 (0.58) | ALDH1A1LMNAMAPTCCR2NOD2 | |
| SCHEMBL10002763 | 0.83 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPTCCR2NOD2 | |
| Hydrochloric Acid SCHEMBL4119324 | 0.82 | CCR2 (0.71) | ALDH1A1LMNAMAPTCCR2NOD2 | |
| SCHEMBL3836440 | 0.81 | ALDH1A1 (0.62) | ALDH1A1LMNAMAPTCCR2NOD2 | |
| SCHEMBL3056166 | 0.81 | ALDH1A1 (0.62) | ALDH1A1LMNAMAPTCCR2NOD2 | |
| SCHEMBL9617940 | 0.81 | NOD2 (0.64) | ALDH1A1LMNAMAPTCCR2NOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253697-A1 | Novel Indole Derivatives, Preparation Thereof as Medicinal Products and Pharmaceutical Compositions, and Especially as KDR Inhibitors | AVENTIS PHARMA S.A. (FR) | 2009-10-08 | — | — | US | disclosed |
| US-20040242559-A1 | Novel indole derivatives, preparation thereof as medicinal products and pharmaceutical compositions, and especially as KDR inhibitors | AVENTIS PHARMA S.A. (FR) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242559-A1 | Novel indole derivatives, preparation thereof as medicinal products and pharmaceutical compositions, and especially as KDR inhibitors | FLT4, KDR, CYP3A4 | ALDH1A1 1515/4885LMNA 4771/4885MAPT 4583/4885 |
| US-20090253697-A1 | Novel Indole Derivatives, Preparation Thereof as Medicinal Products and Pharmaceutical Compositions, and Especially as KDR Inhibitors | KDR, FLT1, FLT4 | ALDH1A1 326/4885LMNA 3126/4885MAPT 3747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.