Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 6/20 | 0.68 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.62 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.62 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.54 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.54 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.53 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.53 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23203469 | 0.83 | MAPK13 (0.73) | NTRK1KCNJ6KCNJ5KCNJ3TSHR | |
| SCHEMBL4130247 | 0.83 | SOAT2 (0.75) | NTRK1KCNJ6KCNJ5KCNJ3TSHR | |
| SCHEMBL16595134 | 0.82 | NTRK1 (1.00) | NTRK1KCNJ6KCNJ5KCNJ3TSHR | |
| SCHEMBL4137645 | 0.81 | MEN1 (0.58) | EPHX1ALDH1A1HTT | |
| SCHEMBL4132285 | 0.81 | MEN1 (0.58) | EPHX1ALDH1A1HTT | |
| SCHEMBL4135897 | 0.81 | MEN1 (0.58) | EPHX1ALDH1A1HTT | |
| SCHEMBL4132087 | 0.81 | MEN1 (0.58) | EPHX1ALDH1A1HTT | |
| SCHEMBL4145849 | 0.81 | MEN1 (0.58) | EPHX1ALDH1A1HTT | |
| SCHEMBL4127216 | 0.81 | MEN1 (0.58) | EPHX1ALDH1A1HTT | |
| SCHEMBL4136924 | 0.81 | MEN1 (0.58) | EPHX1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090192192-A1 | INHIBITORS OF BIOFILM FORMATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA | TOUCH BIONICS LIMITED (GB) | 2009-07-30 | — | — | US | disclosed |
| US-20090192192-A1 | INHIBITORS OF BIOFILM FORMATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA | TOUCH BIONICS LIMITED (GB) | 2009-07-30 | — | — | US | disclosed |
| US-20090192192-A1 | INHIBITORS OF BIOFILM FORMATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA | TOUCH BIONICS LIMITED (GB) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192192-A1 | INHIBITORS OF BIOFILM FORMATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA | PGLS, TFPI, Q6ZSR9 | NTRK1 4159/4885KCNJ6 529/4885KCNJ5 468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.