Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 4/20 | 0.75 |
| ▸ | SOAT1 | P35610 | 4/20 | 0.75 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.58 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.58 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16171341 | 0.86 | SOAT2 (1.00) | SOAT2SOAT1ALDH1A1HTTLMNA | |
| SCHEMBL19448012 | 0.86 | SOAT2 (1.00) | SOAT2SOAT1ALDH1A1HTTLMNA | |
| SCHEMBL16171342 | 0.86 | SOAT2 (1.00) | SOAT2SOAT1ALDH1A1HTTLMNA | |
| SCHEMBL13811056 | 0.85 | SOAT2 (0.59) | SOAT2SOAT1NTRK1ALDH1A1HTT | |
| SCHEMBL4125510 | 0.83 | NTRK1 (0.68) | SOAT2SOAT1NTRK1ALDH1A1HTT | |
| SCHEMBL15717788 | 0.83 | NTRK1 (0.85) | NTRK1ALDH1A1HTTL3MBTL1ATM | |
| SCHEMBL7936656 | 0.81 | NTRK1 (0.72) | NTRK1ALDH1A1HTTL3MBTL1ATM | |
| SCHEMBL16595134 | 0.79 | NTRK1 (1.00) | NTRK1ALDH1A1HTTL3MBTL1ATM | |
| SCHEMBL21775898 | 0.78 | SOAT2 (0.51) | SOAT2SOAT1NTRK1ALDH1A1HTT | |
| SCHEMBL21775901 | 0.78 | SOAT2 (0.51) | SOAT2SOAT1NTRK1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090192192-A1 | INHIBITORS OF BIOFILM FORMATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA | TOUCH BIONICS LIMITED (GB) | 2009-07-30 | — | — | US | disclosed |
| US-20090192192-A1 | INHIBITORS OF BIOFILM FORMATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA | TOUCH BIONICS LIMITED (GB) | 2009-07-30 | — | — | US | disclosed |
| US-20090192192-A1 | INHIBITORS OF BIOFILM FORMATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA | TOUCH BIONICS LIMITED (GB) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192192-A1 | INHIBITORS OF BIOFILM FORMATION OF GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA | PGLS, TFPI, Q6ZSR9 | SOAT2 3808/4885SOAT1 3290/4885NTRK1 4159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.