Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | TSHR | P16473 | 9/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 9/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9963184 | 0.89 | ALDH1A1 (0.51) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL23136906 | 0.85 | ALDH1A1 (0.57) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL23136905 | 0.85 | ALDH1A1 (0.60) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL9965906 | 0.78 | ALDH1A1 (0.40) | ALDH1A1TSHRMEN1KMT2ANPSR1 | |
| Hydrochloric Acid SCHEMBL22528409 | 0.76 | ALDH1A1 (0.39) | ALDH1A1TSHRMEN1KMT2ANPSR1 | |
| SCHEMBL24969367 | 0.74 | MEN1 (0.37) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL22541489 | 0.73 | ALDH1A1 (0.39) | ALDH1A1TSHRMEN1KMT2AMAPT | |
| SCHEMBL3600694 | 0.70 | CCR5 (0.40) | — | |
| SCHEMBL1514757 | 0.69 | MEN1 (0.39) | ALDH1A1TSHRMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL16992153 | 0.68 | MEN1 (0.41) | ALDH1A1TSHRMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209578-A1 | CHEMICAL COMPOUNDS | PFIZER INC | 2009-08-20 | — | — | US | disclosed |
| US-20090209578-A1 | CHEMICAL COMPOUNDS | PFIZER INC | 2009-08-20 | — | — | US | disclosed |
| US-20090209578-A1 | CHEMICAL COMPOUNDS | PFIZER INC | 2009-08-20 | — | — | US | disclosed |
| EP-1963303-A2 | CHEMICAL COMPOUNDS | Pfizer Limited (GB) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007066201-A2 | CHEMICAL COMPOUNDS | PFIZER LIMITED (GB) | 2007-06-14 | — | — | WO | disclosed |
| WO-2007066201-A2 | CHEMICAL COMPOUNDS | PFIZER LIMITED (GB) | 2007-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209578-A1 | CHEMICAL COMPOUNDS | CCR5, CXCR3, CXCR1 | ALDH1A1 1442/4885TSHR 859/4885LMNA 4759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.