Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
| ▸ | PRCP | P42785 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
| ▸ | NPY1R | P25929 | 2/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4048356 | 0.84 | SIGMAR1 (0.47) | SLC6A2SLC6A4SLC6A3SIGMAR1GRIN2D | |
| SCHEMBL4048354 | 0.78 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3SIGMAR1GRIN2D | |
| SCHEMBL4112299 | 0.78 | TSHR (0.39) | SLC6A2SLC6A4SLC6A3SIGMAR1OPRL1 | |
| SCHEMBL7388493 | 0.77 | SIGMAR1 (0.73) | SLC6A2SLC6A4SLC6A3SIGMAR1GRIN2D | |
| SCHEMBL19262558 | 0.74 | SIGMAR1 (0.50) | SLC6A2SLC6A4SLC6A3SIGMAR1GRIN2D | |
| SCHEMBL10819368 | 0.74 | GRIN2D (0.50) | SLC6A2SLC6A4SLC6A3SIGMAR1GRIN2D | |
| SCHEMBL27678993 | 0.74 | SIGMAR1 (0.50) | SLC6A2SLC6A4SLC6A3SIGMAR1GRIN2D | |
| SCHEMBL734607 | 0.73 | SIGMAR1 (0.49) | SLC6A2SLC6A4SLC6A3SIGMAR1GRIN2D | |
| SCHEMBL3941642 | 0.73 | SIGMAR1 (0.49) | SLC6A2SLC6A4SLC6A3SIGMAR1GRIN2D | |
| SCHEMBL27714919 | 0.72 | SIGMAR1 (0.45) | SLC6A2SLC6A4SLC6A3SIGMAR1GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | SULT2A1, STS, SULT1A1 | SLC6A2 1720/4885SLC6A4 986/4885SLC6A3 1698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.