Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 5/20 | 0.51 |
| ▸ | MAOA | P21397 | 13/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL412083 | 0.91 | TDO2 (0.40) | CALML3MAOACYP2C19CYP2C9MAOB | |
| SCHEMBL411619 | 0.89 | GRM2 (0.40) | CALML3 | |
| SCHEMBL411618 | 0.89 | CALML3 (0.49) | CALML3MAOACYP2C19CYP2C9MAOB | |
| SCHEMBL412767 | 0.88 | MAOA (0.49) | CALML3MAOACYP2C19CYP2C9MAOB | |
| SCHEMBL411080 | 0.88 | TDO2 (0.40) | CALML3MAOACYP2C19CYP2C9MAOB | |
| SCHEMBL411595 | 0.86 | CALML3 (0.68) | CALML3MAOACYP2C19CYP2C9MAOB | |
| SCHEMBL15828775 | 0.86 | CALML3 (0.46) | CALML3MAOACYP2C19CYP2C9MAOB | |
| SCHEMBL15828767 | 0.85 | CALML3 (0.47) | CALML3MAOACYP2C19CYP2C9MAOB | |
| SCHEMBL463398 | 0.85 | MAOA (0.60) | CALML3MAOACYP2C19CYP2C9MAOB | |
| SCHEMBL412829 | 0.85 | CALML3 (0.53) | CALML3MAOACYP2C19CYP2C9MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065170-A1 | Antimicrobial Cyclocarbonyl Heterocyclic Compounds For Treatment Of Bacterial Infections | MICURX PHARMACEUTICALS, INC. (KY) | 2012-03-15 | — | — | US | disclosed |
| US-20120065170-A1 | Antimicrobial Cyclocarbonyl Heterocyclic Compounds For Treatment Of Bacterial Infections | MICURX PHARMACEUTICALS, INC. (KY) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065170-A1 | Antimicrobial Cyclocarbonyl Heterocyclic Compounds For Treatment Of Bacterial Infections | NISCH, SI, VIP | CALML3 1652/4885MAOA 853/4885CYP2C19 65/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.