Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 18/20 | 0.41 |
| ▸ | PPARA | Q07869 | 17/20 | 0.41 |
| ▸ | PPARG | P37231 | 17/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4126821 | 0.76 | ACHE (0.40) | PPARDPPARAPPARG | |
| SCHEMBL13597386 | 0.75 | PPARD (0.44) | PPARDPPARAPPARGNR1H2NR1H3 | |
| SCHEMBL13596407 | 0.74 | CSF1R (0.41) | PPARDPPARAPPARG | |
| SCHEMBL4126911 | 0.70 | — | — | |
| SCHEMBL4126887 | 0.69 | NR1H2 (0.33) | PPARDPPARAPPARGNR1H2NR1H3 | |
| SCHEMBL706843 | 0.68 | SMYD2 (0.40) | — | |
| SCHEMBL20983501 | 0.66 | CYP3A4 (0.33) | — | |
| SCHEMBL4113718 | 0.65 | EDNRA (0.37) | — | |
| SCHEMBL4112472 | 0.64 | — | — | |
| SCHEMBL13596012 | 0.64 | ALDH1A1 (0.39) | PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
| US-20090318690-A1 | Benzisoxazole Compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
| EP-2017275-A1 | BENZISOXAZOLE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2009-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318690-A1 | Benzisoxazole Compound | NR1I2, NR1I3, NR0B1 | PPARD 924/4885PPARA 911/4885PPARG 498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.