SCHEMBL412769

SCHEMBL412769

CC1=CC=C(N)C([N+](=O)[O-])C1(C)[N+](=O)[O-]

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10904104 0.69 ACHE (0.31) ALDH1A1CYP3A4TDP1
SCHEMBL3130595 0.67 CA12 (0.33)
SCHEMBL10444149 0.67
SCHEMBL11595786 0.66 TSHR (0.32) ALDH1A1CYP3A4TDP1
SCHEMBL4536565 0.62 TSHR (0.31)
SCHEMBL9712523 0.61
SCHEMBL29126606 0.58
SCHEMBL21351629 0.57 NOS3 (0.30)
SCHEMBL11742503 0.56
SCHEMBL28803218 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12543674-B2 Embryogenesis factors for cellular reprogramming of a plant cell PIONEER HI-BRED INTERNATIONAL, INC. (US) 2026-02-10 US disclosed
US-20250115927-A1 METHODS FOR CLONAL PLANT PRODUCTION PIONEER HI-BRED INTERNATIONAL, INC. (US) 2025-04-10 US disclosed
US-20250115924-A1 SYSTEMS AND METHODS FOR CELLULAR REPROGRAMMING OF A PLANT CELL PIONEER HI-BRED INTERNATIONAL, INC. (US) 2025-04-10 US disclosed
US-12146147-B2 Methods for clonal plant production PIONEER HI-BRED INTERNATIONAL, INC. (US) 2024-11-19 US disclosed
US-20240002877-A1 PARTHENOGENESIS FACTORS AND METHODS OF USING SAME PIONEER HI-BRED INTERNATIONAL, INC. (US) 2024-01-04 US disclosed
US-20230407324-A1 DOUBLED HAPLOID INDUCER PIONEER HI-BRED INTERNATIONAL, INC. (US) 2023-12-21 US disclosed
US-20230203516-A1 SYSTEMS AND METHODS FOR CELLULAR REPROGRAMMING OF A PLANT CELL PIONEER HI-BRED INTERNATIONAL, INC. (US) 2023-06-29 US disclosed
US-20230189734-A1 EMBRYOGENESIS FACTORS FOR CELLULAR REPROGRAMMING OF A PLANT CELL PIONEER HI-BRED INTERNATIONAL, INC. (US) 2023-06-22 US disclosed
US-20230107598-A1 SORGHUM DOUBLED HAPLOID PRODUCTION SYSTEM PIONEER HI-BRED INTERNATIONAL, INC. (US) 2023-04-06 US disclosed
US-11447786-B2 Systems and methods for cellular reprogramming of a plant cell PIONEER HI-BRED INTERNATIONAL, INC. 2022-09-20 US disclosed
US-20200263189-A1 SYSTEMS AND METHODS FOR CELLULAR REPROGRAMMING OF A PLANT CELL PIONEER HI-BRED INTERNATIONAL, INC. (US) 2020-08-20 US disclosed
US-20150307889-A1 HAPLOID MAIZE TRANSFORMATION CORTEVA AGRISCIENCE LLC 2015-10-29 US disclosed
US-9121032-B2 Selective ablation of diploid embryos E I DU PONT DE NEMOURS AND COMPANY (US) 2015-09-01 US disclosed
US-8859846-B2 Doubling of chromosomes in haploid embryos E. I. DU PONT DE NEMOURS AND COMPANY (US) 2014-10-14 US disclosed
US-20130205438-A1 DOUBLING OF CHROMOSOMES IN HAPLOID EMBRYOS PIONEER HI BRED INTERNATIONAL INC (US) 2013-08-08 US disclosed
US-20120311736-A1 SELECTIVE ABLATION OF DIPLOID EMBRYOS E.I. du Pont de Nemours and Company and Pioneer Hi-Bred International 2012-12-06 US disclosed
US-8269061-B2 Selective ablation of diploid embryos E.I. du Pont de Nmeours and Company (US) 2012-09-18 US disclosed
US-20120023612-A1 SELECTIVE ABLATION OF DIPLOID EMBRYOS E. I. DU PONT DE NEMOURS AND COMPANY AND PIONEER HI-BRED INTERNATIONAL, INC. (US) 2012-01-26 US disclosed
US-20080216191-A1 Pollinating silks of maize ear, contacting haploid embryo with chromosome doubling agent (colchicine), propagate cells; generating homozygosity in plants PIONEER HI-BRED INTERNATIONAL, INC. (US) 2008-09-04 US disclosed
US-20080189801-A1 Selective Ablation of Diploid Embryos PIONNER HI-BRED INTERNATIONAL, INC. 2008-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12543674-B2 Embryogenesis factors for cellular reprogramming of a plant cell CCNB2, CCNB1, CCNB3 ALDH1A1 4751/4885CYP3A4 4593/4885TDP1 3165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.