Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4709292 | 0.76 | AOC3 (0.38) | KDM4EIDO1KMT2AMEN1 | |
| SCHEMBL20590031 | 0.69 | — | — | |
| SCHEMBL4138249 | 0.68 | NPC1 (0.42) | KDM4E | |
| SCHEMBL24516608 | 0.67 | TEAD4 (0.36) | KDM4EIDO1HDAC3HDAC4HDAC1 | |
| SCHEMBL510447 | 0.67 | LMNA (0.33) | KDM4EIDO1KMT2AMEN1 | |
| SCHEMBL597442 | 0.66 | IDO1 (0.46) | KDM4EIDO1TDO2HDAC3HDAC4 | |
| SCHEMBL3229698 | 0.66 | NR4A1 (0.41) | KDM4EHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL22140465 | 0.65 | — | — | |
| SCHEMBL21383098 | 0.63 | — | — | |
| SCHEMBL1964902 | 0.63 | MEN1 (0.50) | IDO1TDO2KMT2AATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247772-A1 | Method for the Preparation of Escitalopram | H. LUNDBECK A/S (DK) | 2009-10-01 | — | — | US | claimed |
| US-20090247772-A1 | Method for the Preparation of Escitalopram | H. LUNDBECK A/S (DK) | 2009-10-01 | — | — | US | disclosed |
| US-20090247772-A1 | Method for the Preparation of Escitalopram | H. LUNDBECK A/S (DK) | 2009-10-01 | — | — | US | disclosed |
| US-20090247772-A1 | Method for the Preparation of Escitalopram | H. LUNDBECK A/S (DK) | 2009-10-01 | — | — | US | disclosed |
| WO-2007054105-A2 | METHOD FOR THE PREPARATION OF ESCITALOPRAM | H. LUNDBECK A/S (DK) | 2007-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247772-A1 | Method for the Preparation of Escitalopram | SLC6A4, SLC6A2, SLC6A3 | KDM4E 1368/4885IDO1 689/4885TDO2 476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.