SCHEMBL41299

SCHEMBL41299

c1csc(-c2ccc(-c3cccs3)c3nsnc23)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.43
ALDH1A1 P00352 4/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
MAPT P10636 2/20 0.43
HPGD P15428 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
TDO2 P48775 1/20 0.43
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
ATM Q13315 1/20 0.40
CYP3A4 P08684 2/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2E1 P05181 1/20 0.39
CYP2A6 P11509 1/20 0.39
CYP2B6 P20813 1/20 0.39
HSD17B10 Q99714 3/20 0.38
POLB P06746 1/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12587621 0.92 DPP4 (0.40) KDM4EALDH1A1MEN1KMT2AMAPT
SCHEMBL4411262 0.89 KDM4E (0.39) KDM4EALDH1A1MEN1KMT2AMAPT
SCHEMBL20610387 0.89 DPP4 (0.45) KDM4EALDH1A1MEN1KMT2AMAPT
SCHEMBL12587611 0.89 POLB (0.40) KDM4EALDH1A1MEN1KMT2AMAPT
SCHEMBL13892125 0.89 MGAM (0.42) KDM4EALDH1A1MEN1KMT2AMAPT
SCHEMBL14685994 0.87 DPP4 (0.46) KDM4EALDH1A1MEN1KMT2AMAPT
SCHEMBL15931487 0.86 CYP2E1 (0.39) KDM4EALDH1A1MEN1KMT2AMAPT
SCHEMBL10330347 0.86 ALDH1A1 (0.36) KDM4EALDH1A1MEN1KMT2AMAPT
SCHEMBL20428786 0.85 DPP4 (0.45) KDM4EALDH1A1MEN1KMT2AMAPT
SCHEMBL4755025 0.85 RAB9A (0.35) KDM4EALDH1A1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 826 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260028527-A1 Fluorescent Particles LIFE TECHNOLOGIES CORP (US) 2026-01-29 US claimed
US-12460124-B2 Fluorescent particles Life Technologies Corporation (US) 2025-11-04 US claimed
WO-2025133616-A1 CONJUGATED POLYMER NANOPARTICLE BIOSENSORS STREAM BIO LTD (GB) 2025-06-26 WO claimed
CN-119223941-A Probe for detecting trace trivalent arsenic ions and ECL detector based on probe 苏州大学 2024-12-31 CN claimed
CN-119120003-A Circularly polarized long afterglow material and its prepn and application 华东理工大学 2024-12-13 CN claimed
CN-119020018-A Energy transfer system based on sodium poly-4-styrenesulfonate and preparation method and application thereof 常州大学 2024-11-26 CN claimed
CN-118652679-A Light capturing system based on column arene and cyanostyrene derivative, and preparation method and application thereof 常州大学 2024-09-17 CN claimed
EP-3131957-B1 PROCESS FOR THE IMPREGNATION OF POLYMER SUBSTRATES ENI SPA (IT) 2024-07-10 EP claimed
EP-3277846-B1 OPTICAL PAINTING AND FLUORESCENCE-ACTIVATED SORTING OF ADHERENT CELLS UNIV WASHINGTON (US) 2024-07-10 EP claimed
CN-118267475-A Hybrid semiconductor polymer nanometer therapeutic agent and preparation and application thereof 东华大学 2024-07-02 CN claimed
US-20100255477-A1 METHODS AND COMPOSITIONS FOR ASSAYING A SAMPLE FOR AN AGGREGANT THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-10-07 US claimed
US-7666594-B2 biosensors; cationic polymers; peptide nucleic acids; point mutations; quantitative analysis THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-02-23 US claimed
EP-1838752-A2 CATIONIC CONJUGATED POLYMERS SUITABLE FOR STRAND-SPECIFIC POLYNUCLEOTIDE DETECTION IN HOMOGENEOUS AND SOLID STATE ASSAYS The Regents of the University of California (US) 2007-10-03 EP claimed
US-7217824-B2 Process for preparing a 4,7-bis(5-halothien-2-yl)-2,1,3-benzothiadiazole and a precursor therefor SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-15 US claimed
US-20060204984-A1 biosensors; cationic polymers; peptide nucleic acids; point mutations; quantitative analysis THE REGENTS OF UNIVERSITY OF CALIFORNIA (US) 2006-09-14 US claimed
US-20060183140-A1 Cationic conjugated polymers suitable for strand-specific polynucleotide detection in homogeneous and solid state assays THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-08-17 US claimed
WO-2006083932-A2 METHODS AND COMPOSITIONS FOR AGGREGANT DETECTION THE REGENTS OF THE UNIVERSITY (US) 2006-08-10 WO claimed
WO-2006074471-A2 CATIONIC CONJUGATED POLYMERS SUITABLE FOR STRAND-SPECIFIC POLYNUCLEOTIDE DETECTION IN HOMOGENEOUS AND SOLID STATE ASSAYS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-07-13 WO claimed
WO-2004103981-A1 PROCESS FOR PREPARING A 4,7-BIS(5-HALOTHIEN-2-YL)-2,1,3-BENZOTHIADIAZOLE AND A PRECURSOR THEREFOR DOW GLOBAL TECHNOLOGIES INC. (US) 2004-12-02 WO claimed
US-20040229925-A1 Process for preparing a 4,7-bis(5-halothien-2-yl)-2,1,3-benzothiadiazole and a precursor therefor SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028527-A1 Fluorescent Particles CALD1, FUS, CAPZB KDM4E 4844/4885ALDH1A1 2293/4885MEN1 4007/4885
US-20040229925-A1 Process for preparing a 4,7-bis(5-halothien-2-yl)-2,1,3-benzothiadiazole and a precursor therefor WEE2, WEE1, NOTUM KDM4E 3005/4885ALDH1A1 240/4885MEN1 2395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.