SCHEMBL4411262

SCHEMBL4411262

Brc1ccc(-c2cccs2)c2nsnc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.39
MAPT P10636 4/20 0.39
TDP1 Q9NUW8 3/20 0.39
RAB9A P51151 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
PPARG P37231 1/20 0.39
NCOA2 Q15596 1/20 0.39
NCOA1 Q15788 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
NCOA3 Q9Y6Q9 1/20 0.39
TDO2 P48775 1/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
HPGD P15428 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPK1 P28482 1/20 0.35
GLO1 Q04760 1/20 0.35
NPC1 O15118 2/20 0.34
ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL41299 0.89 KDM4E (0.43) KDM4EMAPTTDP1RAB9ASMN1; SMN2
SCHEMBL12587621 0.82 DPP4 (0.40) KDM4EMAPTTDP1RAB9ATDO2
SCHEMBL4755025 0.82 RAB9A (0.35) KDM4EMAPTTDP1RAB9ASMN1; SMN2
SCHEMBL13892125 0.79 MGAM (0.42) KDM4EMAPTTDP1RAB9ASMN1; SMN2
SCHEMBL20610387 0.79 DPP4 (0.45) KDM4EMAPTTDP1RAB9ASMN1; SMN2
SCHEMBL12587611 0.79 POLB (0.40) KDM4EMAPTTDP1RAB9ASMN1; SMN2
SCHEMBL20428806 0.79 MAPT (0.40) KDM4EMAPTMEN1KMT2AL3MBTL1
SCHEMBL15707541 0.78 TDO2 (0.39) KDM4EMAPTTDP1RAB9ASMN1; SMN2
SCHEMBL14685994 0.77 DPP4 (0.46) KDM4EMAPTTDP1RAB9ASMN1; SMN2
SCHEMBL15931487 0.77 CYP2E1 (0.39) KDM4EMAPTTDP1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3154988-B1 BORYLATED COMPOUNDS UNIV MANCHESTER (GB) 2019-01-09 EP disclosed
US-9184392-B2 Polymer and organic solar cell including same LG CHEM, LTD. (KR) 2015-11-10 US disclosed
US-9184392-B2 Polymer and organic solar cell including same LG CHEM, LTD. (KR) 2015-11-10 US disclosed
US-9184392-B2 Polymer and organic solar cell including same LG CHEM, LTD. (KR) 2015-11-10 US disclosed
US-20150171328-A1 FLUORESCENT COMPOUNDS OF THE BORON THIENYLDIPYRROMETHENE TYPE, AND THEIR USE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2015-06-18 US disclosed
US-20150171328-A1 FLUORESCENT COMPOUNDS OF THE BORON THIENYLDIPYRROMETHENE TYPE, AND THEIR USE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2015-06-18 US disclosed
EP-2813526-A1 POLYMER AND ORGANIC SOLAR CELL INCLUDING SAME LG Chem, Ltd. (KR) 2014-12-17 EP disclosed
US-20140290747-A1 POLYMER AND ORGANIC SOLAR CELL INCLUDING SAME LG CHEM, LTD. (KR) 2014-10-02 US disclosed
US-20140290747-A1 POLYMER AND ORGANIC SOLAR CELL INCLUDING SAME LG CHEM, LTD. (KR) 2014-10-02 US disclosed
US-20140290747-A1 POLYMER AND ORGANIC SOLAR CELL INCLUDING SAME LG CHEM, LTD. (KR) 2014-10-02 US disclosed
WO-2014074027-A1 POLYMERS AND THEIR USE IN PHOTOVOLTAIC DEVICES LANXESS DEUTSCHLAND GMBH (DE) 2014-05-15 WO disclosed
EP-2730632-A1 Polymer compound and its use in photovoltaic devices LANXESS Deutschland GmbH (DE) 2014-05-14 EP disclosed
WO-2013119022-A1 POLYMER AND ORGANIC SOLAR CELL INCLUDING SAME 주식회사 엘지화학 (KR) 2013-08-15 WO disclosed
US-7638594-B2 Conjugated polymers containing spirobifluorene units and the use thereof MERCK PATENT GMBH (DE) 2009-12-29 US disclosed
US-7323533-B2 Conjugated polymers containing spirobifluorene units and the use thereof COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2008-01-29 US disclosed
US-20070265473-A1 CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2007-11-15 US disclosed
EP-1427768-B1 CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF MERCK PATENT GMBH (DE) 2007-01-24 EP disclosed
US-20050038223-A1 Conjugated polymers containing spirobifluorene units and the use thereof MERCK PATENT GMBH (DE) 2005-02-17 US disclosed
EP-1427768-A2 CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF Covion Organic Semiconductors GmbH (DE) 2004-06-16 EP disclosed
WO-2003020790-A2 CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2003-03-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150171328-A1 FLUORESCENT COMPOUNDS OF THE BORON THIENYLDIPYRROMETHENE TYPE, AND THEIR USE BTD, DBF4, BRPF1 KDM4E 3920/4885MAPT 1420/4885TDP1 567/4885
US-20070265473-A1 CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF ALDH1A2, SELE, PPOX KDM4E 4836/4885MAPT 1185/4885TDP1 3961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.