Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 10/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4139503 | 0.88 | MEN1 (0.44) | HCRTR1HCRTR2MEN1KMT2AFAAH | |
| SCHEMBL4139508 | 0.88 | MEN1 (0.44) | HCRTR1HCRTR2MEN1KMT2AFAAH | |
| SCHEMBL4135770 | 0.84 | FAAH (0.40) | ALDH1A1FAAHHTR1AHTR7L3MBTL3 | |
| SCHEMBL4147507 | 0.84 | MCHR1 (0.41) | BCHEHTR1AMCHR1 | |
| SCHEMBL4141778 | 0.84 | HRH3 (0.41) | FAAHBCHEL3MBTL3L3MBTL1MCHR1 | |
| SCHEMBL4133564 | 0.77 | HTR1A (0.48) | FAAHHTR1AHTR7L3MBTL3L3MBTL1 | |
| SCHEMBL4141665 | 0.76 | HTR1A (0.44) | FAAHHTR1AHTR7L3MBTL3L3MBTL1 | |
| SCHEMBL4145725 | 0.76 | HTR1A (0.44) | FAAHHTR1AHTR7MCHR1TSHR | |
| SCHEMBL4136657 | 0.74 | HRH3 (0.48) | BCHEHTR1AMCHR1 | |
| SCHEMBL4141092 | 0.74 | BCHE (0.44) | FAAHBCHEL3MBTL3L3MBTL1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163482-A1 | TETRALINES ANTAGONISTS OF THE H-3 RECEPTOR | MCHARDY STANTON FURST | 2009-06-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163482-A1 | TETRALINES ANTAGONISTS OF THE H-3 RECEPTOR | HRH3, HRH4, HRH1 | HCRTR1 20/4885HCRTR2 16/4885MEN1 3359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.