Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4139503 | 0.90 | MEN1 (0.44) | FAAHHTR1AHTR7L3MBTL3L3MBTL1 | |
| SCHEMBL4139508 | 0.90 | MEN1 (0.44) | FAAHHTR1AHTR7L3MBTL3L3MBTL1 | |
| SCHEMBL4664245 | 0.86 | HRH3 (0.34) | FAAHTSHRNPSR1ALDH1A1HSD17B3 | |
| SCHEMBL4130165 | 0.84 | HCRTR1 (0.38) | FAAHHTR1AHTR7L3MBTL3L3MBTL1 | |
| SCHEMBL4133564 | 0.78 | HTR1A (0.48) | FAAHHTR1AHTR7L3MBTL3L3MBTL1 | |
| SCHEMBL4145725 | 0.77 | HTR1A (0.44) | FAAHHTR1AHTR7OPRL1OPRM1 | |
| SCHEMBL4136905 | 0.76 | HTR7 (0.44) | HTR1AHTR7GRIN2BSIGMAR1ALDH1A1 | |
| SCHEMBL4137098 | 0.76 | HTR1A (0.44) | FAAHHTR1AHTR7OPRL1OPRM1 | |
| SCHEMBL4662823 | 0.76 | HTR1A (0.46) | FAAHHTR1AHTR7OPRL1OPRM1 | |
| SCHEMBL4130547 | 0.76 | HTR1A (0.46) | FAAHHTR1AHTR7OPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163482-A1 | TETRALINES ANTAGONISTS OF THE H-3 RECEPTOR | MCHARDY STANTON FURST | 2009-06-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163482-A1 | TETRALINES ANTAGONISTS OF THE H-3 RECEPTOR | HRH3, HRH4, HRH1 | FAAH 217/4885HTR1A 19/4885HTR7 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.