Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | NOS3 | P29474 | 2/20 | 0.51 |
| ▸ | NOS1 | P29475 | 2/20 | 0.51 |
| ▸ | NOS2 | P35228 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | ACR | P10323 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4124314 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9ANPC1GAANOS3 | |
| SCHEMBL16386126 | 0.80 | MEN1 (0.57) | SMN1; SMN2RAB9ANPC1GAANOS3 | |
| SCHEMBL5472458 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2RAB9ANPC1GAANOS3 | |
| SCHEMBL9644601 | 0.78 | RAB9A (0.68) | SMN1; SMN2RAB9ANPC1GAATSHR | |
| SCHEMBL9644606 | 0.78 | RAB9A (0.68) | SMN1; SMN2RAB9ANPC1GAATSHR | |
| Ethyl Benzoate SCHEMBL5690059 | 0.78 | SMN1; SMN2 (0.59) | SMN1; SMN2RAB9ANPC1GAATSHR | |
| Hydrochloric Acid SCHEMBL9645292 | 0.77 | RAB9A (0.67) | SMN1; SMN2RAB9ANPC1GAATSHR | |
| Hydrochloric Acid SCHEMBL9645282 | 0.77 | RAB9A (0.67) | SMN1; SMN2RAB9ANPC1GAATSHR | |
| Ethyl Benzoate SCHEMBL10906112 | 0.77 | LMNA (0.66) | SMN1; SMN2RAB9ANPC1GAATSHR | |
| Ethyl Benzoate SCHEMBL25388294 | 0.77 | LMNA (0.70) | SMN1; SMN2RAB9ANPC1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511145-B2 | Bicyclic heteroaryl derivatives | GENELABS TECHNOLOGIES, INC. (US) | 2009-03-31 | — | — | US | disclosed |
| US-20090081165-A1 | BICYCLIC HETEROARYL DERIVATIVES | GENELABS TECHNOLOGIES, INC. | 2009-03-26 | — | — | US | disclosed |
| US-20050187390-A1 | Bicyclic heteroaryl derivatives | GENELABS TECHNOLOGIES, INC. | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090081165-A1 | BICYCLIC HETEROARYL DERIVATIVES | HAVCR2, MAVS, ZC3HAV1 | SMN1; SMN2 2019/4885RAB9A 893/4885NPC1 149/4885 |
| US-20050187390-A1 | Bicyclic heteroaryl derivatives | HAVCR2, MAVS, ZC3HAV1 | SMN1; SMN2 2019/4885RAB9A 893/4885NPC1 149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.