SCHEMBL4130437

SCHEMBL4130437

CC(=O)NC1C(O)[C@H](O[C@@H]2OC(CO)[C@H](O)[C@H](O[C@]3(OC=O)C[C@@H](O)[C@@H](C)C([C@H](O)[C@H](O)CO)O3)C2O)[C@H](CO)O[C@H]1OC1[C@@H](OCC2O[C@@H](O[C@@H]3C(CO)O[C@@H](O[C@@H]4C(CO)O[C@@H](C)C(NC(C)=O)[C@H]4O)C(NC(C)=O)[C@H]3O)C(O)[C@@H](O[C@H]3OC(CO)[C@@H](O)C(O)C3O[C@@H]3OC(CO)[C@@H](O[C@@H]4OC(CO)[C@H](O)[C@H](O[C@]5(OC=O)C[C@@H](O)[C@@H](C)C([C@H](O)[C@H](O)CO)O5)C4O)[C@H](O)C3NC(C)=O)[C@@H]2O)OC(CO)[C@@H](O)[C@@H]1O

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ SIGLEC7 Q9Y286 6/20 0.48
▸ MAG P20916 8/20 0.47
▸ SELE P16581 4/20 0.47
▸ SELL P14151 1/20 0.40
▸ SELP P16109 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16312027 1.00 SIGLEC7 (0.48) SIGLEC7MAGSELESELLSELP
SCHEMBL12197063 1.00 SIGLEC7 (0.48) SIGLEC7MAGSELESELLSELP
SCHEMBL17195818 1.00 SIGLEC7 (0.48) SIGLEC7MAGSELESELLSELP
SCHEMBL15849094 1.00 SIGLEC7 (0.48) SIGLEC7MAGSELESELLSELP
SCHEMBL12197067 0.99 SIGLEC7 (0.47) SIGLEC7MAGSELESELLSELP
SCHEMBL16232773 0.99 SIGLEC7 (0.47) SIGLEC7MAGSELESELLSELP
SCHEMBL16312031 0.99 SIGLEC7 (0.47) SIGLEC7MAGSELESELLSELP
SCHEMBL12197073 0.99 SIGLEC7 (0.47) SIGLEC7MAGSELESELLSELP
SCHEMBL16312028 0.99 SIGLEC7 (0.47) SIGLEC7MAGSELESELLSELP
SCHEMBL15849100 0.99 SIGLEC7 (0.47) SIGLEC7MAGSELESELLSELP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9937264-B2 Glycosylated polypeptide and drug composition containing said polypeptide GLYTECH, INC. (JP) 2018-04-10 — — US disclosed
US-9879097-B2 Method for producing activated sugar chain derivative and activated sugar chain derivative produced therefrom GLYTECH, INC. (JP) 2018-01-30 — — US disclosed
US-9802996-B2 Glycosylated polypeptide and drug composition containing said polypeptide GLYTECH, INC. (JP) 2017-10-31 — — US disclosed
US-20170157260-A1 Glycosylated Polypeptide and Drug Composition Containing said Polypeptide GLYTECH, INC. (JP) 2017-06-08 — — US disclosed
US-20160368961-A1 Glycosylated Polypeptide and Drug Composition Containing said Polypeptide GLYTECH, INC. (JP) 2016-12-22 — — US disclosed
US-9441024-B2 Glycosylated polypeptide and drug composition containing said polypeptide GLYTECH, INC. (JP) 2016-09-13 — — US disclosed
US-20160075799-A1 A METHOD FOR PRODUCING ACTIVATED SUGAR CHAIN DERIVATIVE AND ACTIVATED SUGAR CHAIN DERIVATIVE PRODUCED THEREFROM GLYTECH INC (JP) 2016-03-17 — — US disclosed
US-20160052987-A1 POLYPEPTIDE HAVING SIALYLATED SUGAR CHAINS ATTACHED THERETO GLYTECH, INC. (JP) 2016-02-25 — — US disclosed
US-20140315800-A1 Glycosylated Polypeptide and Drug Composition Containing Said Polypeptide GLYTECH, INC. (JP) 2014-10-23 — — US disclosed
US-20120114595-A1 SUGAR CHAIN-ADDED AILIM EXTRACELLULAR DOMAIN AND METHOD FOR PRODUCING SAME OTSUKA CHEMICAL CO., LTD. (JP) 2012-05-10 — — US disclosed
US-20110313136-A1 IgG-Fc FRAGMENT AND PROCESS FOR PRODUCING THE SAME OTSUKA CHEMICAL CO., LTD. (JP) 2011-12-22 — — US disclosed
US-20110195897-A1 GLYCOSYLATED GLP-1 PEPTIDE OTSUKA CHEMICAL CO., LTD. (JP) 2011-08-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110313136-A1 IgG-Fc FRAGMENT AND PROCESS FOR PRODUCING THE SAME FCGR1A, FCGR2A, FCGR3B SIGLEC7 11/4885MAG 332/4885SELE 532/4885
US-20110195897-A1 GLYCOSYLATED GLP-1 PEPTIDE GLP1R, GIPR, IAPP SIGLEC7 102/4885MAG 1399/4885SELE 200/4885
US-20170157260-A1 Glycosylated Polypeptide and Drug Composition Containing said Polypeptide GIPR, SSTR4, SSTR3 SIGLEC7 100/4885MAG 784/4885SELE 428/4885
US-20160052987-A1 POLYPEPTIDE HAVING SIALYLATED SUGAR CHAINS ATTACHED THERETO IFNAR1, FUT4, SIGLEC7 SIGLEC7 3/4885MAG 1739/4885SELE 316/4885
US-20160075799-A1 A METHOD FOR PRODUCING ACTIVATED SUGAR CHAIN DERIVATIVE AND ACTIVATED SUGAR CHAIN DERIVATIVE PRODUCED THEREFROM SI, ASNS, MGAM SIGLEC7 111/4885MAG 2773/4885SELE 3065/4885
US-20120114595-A1 SUGAR CHAIN-ADDED AILIM EXTRACELLULAR DOMAIN AND METHOD FOR PRODUCING SAME SIGLEC7, ENGASE, SIGLEC9 SIGLEC7 1/4885MAG 319/4885SELE 50/4885
US-20160368961-A1 Glycosylated Polypeptide and Drug Composition Containing said Polypeptide GIPR, SSTR3, SSTR4 SIGLEC7 92/4885MAG 766/4885SELE 440/4885
US-20140315800-A1 Glycosylated Polypeptide and Drug Composition Containing Said Polypeptide GIPR, SSTR3, SSTR4 SIGLEC7 92/4885MAG 766/4885SELE 440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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