Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL185901 | 0.91 | — | — | |
| SCHEMBL4925876 | 0.91 | — | — | |
| SCHEMBL4928050 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL6114328 | 0.88 | — | — | |
| Alcohol SCHEMBL9508420 | 0.79 | ALDH1A1 (0.46) | LMNAHTTALDH1A1CYP1A2KDM4E | |
| Alcohol SCHEMBL1401753 | 0.77 | — | — | |
| SCHEMBL10305050 | 0.77 | — | — | |
| Alcohol SCHEMBL21623931 | 0.77 | THRB (0.81) | THRBLMNAHTTALDH1A1TSHR | |
| Alcohol SCHEMBL29055952 | 0.77 | — | — | |
| SCHEMBL9298648 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8920576-B2 | Methods of removing stains and machine dishwashing methods | HENKEL AG & CO. KGAA (DE) | 2014-12-30 | — | — | US | disclosed |
| US-20130146101-A1 | DETERGENTS | HENKEL AG & CO. KGAA (DE) | 2013-06-13 | — | — | US | disclosed |
| US-20090239778-A1 | Cleaning Agent | HENKEL KGAA (DE) | 2009-09-24 | — | — | US | disclosed |
| US-20090165821-A1 | Detergents | HENKEL KGAA (DE) | 2009-07-02 | — | — | US | disclosed |
| US-7424891-B2 | Detergents | HENKEL AG & CO. KGAA (DE) | 2008-09-16 | — | — | US | disclosed |
| US-20070054828-A1 | Detergents | HENKEL KGAA (DE) | 2007-03-08 | — | — | US | disclosed |
| US-20070054829-A1 | Detergents | HENKEL KGAA (DE) | 2007-03-08 | — | — | US | disclosed |