Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11738692 | 0.78 | — | — | |
| SCHEMBL8675677 | 0.70 | — | — | |
| SCHEMBL4134871 | 0.70 | KDM4E (0.33) | POLB | |
| SCHEMBL8970670 | 0.66 | GABRA1 (0.38) | CYP3A4ALOX15GABRA1GABRB2POLB | |
| SCHEMBL22355711 | 0.65 | GABRA1 (0.54) | MEN1KMT2AGABRA1GABRB2 | |
| SCHEMBL4140872 | 0.65 | ALOX5 (0.41) | MEN1KMT2ACYP3A4ALOX15GABRA1 | |
| SCHEMBL4132560 | 0.65 | — | — | |
| SCHEMBL6846462 | 0.64 | GABRA1 (0.38) | MEN1KMT2ACYP3A4ALOX15GABRA1 | |
| SCHEMBL5849191 | 0.62 | GABRA1 (0.45) | MEN1KMT2ACYP3A4GABRA1GABRB2 | |
| SCHEMBL14816432 | 0.62 | GABRA1 (0.36) | MEN1KMT2ACYP3A4ALOX15GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027101-A1 | TRISUBSTITUTED FURAN DERIVATIVES AS FRAGRANCES AND AROMA SUBSTANCES | Symrise GmbH & Co. KG (DE) | 2009-02-25 | — | — | EP | claimed |
| WO-2007131834-A1 | TRISUBSTITUTED FURAN DERIVATIVES AS FRAGRANCES AND AROMA SUBSTANCES | SYMRISE GMBH & CO. KG (DE) | 2007-11-22 | — | — | WO | claimed |
| EP-2027101-A1 | TRISUBSTITUTED FURAN DERIVATIVES AS FRAGRANCES AND AROMA SUBSTANCES | Symrise GmbH & Co. KG (DE) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007131834-A1 | TRISUBSTITUTED FURAN DERIVATIVES AS FRAGRANCES AND AROMA SUBSTANCES | SYMRISE GMBH & CO. KG (DE) | 2007-11-22 | — | — | WO | disclosed |