Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 8/20 | 0.37 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.37 |
| ▸ | CCR1 | P32246 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4135071 | 0.93 | TRPV4 (0.39) | TRPV4GSTO1CCR1GAAPKM | |
| SCHEMBL4129734 | 0.93 | TRPV4 (0.39) | TRPV4GSTO1CCR1GAAPKM | |
| SCHEMBL4129723 | 0.93 | TRPV4 (0.39) | TRPV4GSTO1CCR1GAAPKM | |
| SCHEMBL4148627 | 0.91 | BMP1 (0.37) | TRPV4GSTO1CCR1PKM | |
| SCHEMBL4148621 | 0.91 | BMP1 (0.37) | TRPV4GSTO1CCR1PKM | |
| SCHEMBL4129226 | 0.86 | TRPV4 (0.41) | TRPV4GSTO1CCR1GAAPKM | |
| SCHEMBL4135082 | 0.86 | TRPV4 (0.41) | TRPV4GSTO1CCR1GAAPKM | |
| SCHEMBL4139740 | 0.84 | PTGES (0.37) | TRPV4 | |
| SCHEMBL4139745 | 0.84 | PTGES (0.37) | TRPV4 | |
| SCHEMBL4139634 | 0.84 | TRPV4 (0.39) | TRPV4GSTO1CCR1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105259-A1 | Acyclic 1,4-Diamines and Uses Thereof | SMITHKLINE BEECHAM CORPORATION | 2009-04-23 | — | — | US | disclosed |
| US-20090105259-A1 | Acyclic 1,4-Diamines and Uses Thereof | SMITHKLINE BEECHAM CORPORATION | 2009-04-23 | — | — | US | disclosed |
| US-20090105259-A1 | Acyclic 1,4-Diamines and Uses Thereof | SMITHKLINE BEECHAM CORPORATION | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105259-A1 | Acyclic 1,4-Diamines and Uses Thereof | TRPV4, TRPC4, TRPV1 | TRPV4 1/4885GSTO1 4156/4885CCR1 766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.