Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 17/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13848566 | 1.00 | CCR5 (0.62) | CCR5KCNH2OPRM1 | |
| SCHEMBL4123919 | 0.82 | CCR5 (0.81) | CCR5KCNH2OPRM1 | |
| SCHEMBL4123915 | 0.82 | CCR5 (0.81) | CCR5KCNH2OPRM1 | |
| SCHEMBL4208078 | 0.77 | CCR5 (0.65) | CCR5KCNH2 | |
| SCHEMBL4189593 | 0.77 | CCR5 (0.66) | CCR5KCNH2OPRM1 | |
| SCHEMBL4203682 | 0.75 | CCR5 (0.64) | CCR5KCNH2OPRM1 | |
| SCHEMBL4191796 | 0.74 | CCR5 (0.75) | CCR5KCNH2 | |
| SCHEMBL13853328 | 0.72 | CCR5 (0.56) | CCR5KCNH2OPRM1 | |
| SCHEMBL4203508 | 0.71 | CCR5 (0.69) | CCR5KCNH2 | |
| SCHEMBL13853347 | 0.70 | CCR5 (0.69) | CCR5KCNH2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124636-A1 | CHEMICAL COMPOUNDS | PFIZER INC. | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124636-A1 | CHEMICAL COMPOUNDS | CCR5, CXCR3, CX3CR1 | CCR5 1/4885KCNH2 810/4885OPRM1 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.