SCHEMBL4131776

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4147183	0.95	IL6 (0.50)	IL6MAPTKDM4EALDH1A1APAF1
	SCHEMBL4580308	0.94	IL6 (0.46)	IL6KMT2AMEN1ESR1MAPT
	SCHEMBL4582096	0.92	IL6 (0.52)	IL6KMT2AMEN1MAPTKDM4E
	SCHEMBL4580706	0.91	IL6 (0.48)	IL6KMT2AMEN1MAPTKDM4E
	SCHEMBL4139325	0.91	IL6 (0.47)	IL6KMT2AMEN1MAPTKDM4E
	SCHEMBL4581523	0.90	IL6 (0.47)	IL6KMT2AMEN1MAPTKDM4E
	SCHEMBL4582119	0.89	IL6 (0.46)	IL6KMT2AMEN1ESR1MAPT
	SCHEMBL4580605	0.89	IL6 (0.46)	IL6KMT2AMAPTKDM4EALDH1A1
	SCHEMBL4129536	0.89	IL6 (0.46)	IL6KMT2AMEN1MAPTKDM4E
	SCHEMBL4581438	0.89	IL6 (0.46)	IL6KMT2AMEN1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.