Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4132228 | 0.77 | RAPGEF4 (0.47) | RAPGEF4FFAR4 | |
| SCHEMBL13800794 | 0.77 | RAPGEF4 (0.47) | RAPGEF4FFAR4 | |
| SCHEMBL4143318 | 0.73 | RAPGEF4 (0.55) | RAPGEF4FFAR4 | |
| SCHEMBL5379353 | 0.73 | RAPGEF4 (0.55) | RAPGEF4FFAR4 | |
| SCHEMBL13800727 | 0.73 | RAPGEF4 (0.55) | RAPGEF4FFAR4 | |
| SCHEMBL1465604 | 0.72 | RAPGEF4 (0.38) | RAPGEF4 | |
| SCHEMBL5383394 | 0.68 | RAPGEF4 (0.47) | RAPGEF4FFAR4 | |
| SCHEMBL4136434 | 0.67 | PTGS2 (0.43) | RAPGEF4 | |
| SCHEMBL4130947 | 0.67 | RAPGEF4 (0.73) | RAPGEF4FFAR4 | |
| SCHEMBL22814187 | 0.66 | RAPGEF4 (1.00) | RAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163740-A1 | LIGANDS FOR METALS AS CATALYSTS FOR CARBON-CARBON BOND FORMATION | NATIONAL SUN YAT-SEN UNIVERSITY | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163740-A1 | LIGANDS FOR METALS AS CATALYSTS FOR CARBON-CARBON BOND FORMATION | NCOR2, OXGR1, NCOR1 | RAPGEF4 3059/4885FFAR4 314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.