Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850176 | 0.83 | ALDH1A1 (0.31) | ALDH1A1KMT2AALOX12RECQL | |
| SCHEMBL1921293 | 0.77 | RAPGEF4 (0.57) | PTGS2RAPGEF4CXCL8DHODHALDH1A1 | |
| SCHEMBL12257142 | 0.77 | ALDH1A1 (0.46) | PTGS2ALDH1A1KMT2AMAPTALOX12 | |
| SCHEMBL3947196 | 0.76 | PTGS2 (0.46) | PTGS2RAPGEF4CXCL8DHODHALDH1A1 | |
| SCHEMBL4800221 | 0.75 | RAPGEF4 (0.55) | PTGS2RAPGEF4ALDH1A1KMT2AMAPT | |
| SCHEMBL7561832 | 0.75 | TSHR (0.43) | ALDH1A1 | |
| SCHEMBL17529903 | 0.71 | TRPA1 (0.39) | RAPGEF4ALDH1A1MAPT | |
| SCHEMBL30636793 | 0.71 | SCN4A (0.39) | ALDH1A1 | |
| SCHEMBL4124328 | 0.71 | MAPT (0.49) | ALDH1A1KMT2AMAPTHTT | |
| SCHEMBL23193120 | 0.70 | PTGS2 (0.50) | PTGS2RAPGEF4CXCL8DHODHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163740-A1 | LIGANDS FOR METALS AS CATALYSTS FOR CARBON-CARBON BOND FORMATION | NATIONAL SUN YAT-SEN UNIVERSITY | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163740-A1 | LIGANDS FOR METALS AS CATALYSTS FOR CARBON-CARBON BOND FORMATION | NCOR2, OXGR1, NCOR1 | PTGS2 718/4885RAPGEF4 3059/4885CXCL8 3817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.