SCHEMBL4132084

SCHEMBL4132084

O=C(NN1C(=O)CCC1=O)ON1C(=O)CCC1=O

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
PARL Q9H300 1/20 0.32
MGLL Q99685 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19154174 0.85 PARL (0.33) KDM4EPARLMGLL
SCHEMBL15528690 0.80 KDM4E (0.42) KDM4E
SCHEMBL27827821 0.78 PARL (0.34) PARLMGLL
SCHEMBL23126429 0.77
SCHEMBL8768378 0.77 MGLL (0.34) MGLL
SCHEMBL352074 0.77 CHRM1 (0.33) MGLL
SCHEMBL30029276 0.76 MGLL (0.33) KDM4EPARLMGLL
SCHEMBL30242949 0.73 MGLL (0.33) PARLMGLL
SCHEMBL13059465 0.73 MGLL (0.31) MGLL
SCHEMBL14698703 0.73 MGLL (0.35) PARLMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210011014-A1 DETECTION AND ASSAY DEVICES AND METHODS OF MAKING AND USING THE SAME HUCKNALL, ANGUS 2021-01-14 US disclosed
US-20190285623-A1 DETECTION AND ASSAY DEVICES AND METHODS OF MAKING AND USING THE SAME Sentilus Holdco LLC (US) 2019-09-19 US disclosed
US-10288607-B2 Detection and assay devices and methods of making and using the same Sentilus Holdco LLC (US) 2019-05-14 US disclosed
US-20140228249-A1 Detection and Assay Devices and Methods of Making and Using the Same SENTILUS, INC. (US) 2014-08-14 US disclosed
US-8796184-B2 Detection assay devices and methods of making and using the same SENTILUS, INC. (US) 2014-08-05 US disclosed
US-20090247424-A1 DETECTION ASSAY DEVICES AND METHODS OF MAKING AND USING THE SAME DUKE UNIVERSITY (US) 2009-10-01 US disclosed