SCHEMBL4132764

SCHEMBL4132764

C=CC(=O)Oc1ccc(C(=O)c2ccc(OC(=O)C=C)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.55
ELANE P08246 13/20 0.52
STS P08842 1/20 0.44
SRD5A2 P31213 1/20 0.42
MEN1 O00255 1/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
MAPK1 P28482 1/20 0.42
RAB9A P51151 1/20 0.42
KMT2A Q03164 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39494 0.92 ELANE (0.65) THRBELANESTSSRD5A2MEN1
SCHEMBL5351776 0.91 ELANE (0.58) THRBELANESRD5A2MEN1LMNA
SCHEMBL31302864 0.91 KMT2A (0.50) THRBELANEMEN1LMNAMAPT
SCHEMBL2402039 0.91 MAPT (0.58) THRBELANEMEN1LMNAMAPT
SCHEMBL2403761 0.91 LMNA (0.58) THRBELANESRD5A2MEN1LMNA
SCHEMBL2587522 0.89 THRB (0.64) THRBELANEMEN1LMNAMAPT
SCHEMBL23064193 0.88 ELANE (0.59) THRBELANESTSSRD5A2MEN1
Benzophenone SCHEMBL28419640 0.88 SRD5A2 (0.60) ELANESRD5A2MEN1KMT2A
SCHEMBL25041907 0.87 THRB (0.55) THRBELANEMEN1MAPTMAPK1
SCHEMBL4526045 0.86 HPGD (0.61) THRBELANEMEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090250670-A1 PHOTOCHROMIC FILMS AND METHOD FOR MANUFACTURING THE SAME HYUNDAI MOTOR COMPANY (KR) 2009-10-08 US claimed
EP-2656144-B1 A CURABLE JETTABLE FLUID FOR MAKING A FLEXOGRAPHIC PRINTING MASTER AGFA NV (BE) 2020-06-24 EP disclosed
US-20130269558-A1 CURABLE JETTABLE FLUID FOR MAKING A FLEXOGRAPHIC PRINTING MASTER AGFA GRAPHICS NV (BE) 2013-10-17 US disclosed
US-20130269558-A1 CURABLE JETTABLE FLUID FOR MAKING A FLEXOGRAPHIC PRINTING MASTER AGFA GRAPHICS NV (BE) 2013-10-17 US disclosed
US-20090250670-A1 PHOTOCHROMIC FILMS AND METHOD FOR MANUFACTURING THE SAME HYUNDAI MOTOR COMPANY (KR) 2009-10-08 US disclosed
US-4329360-A Benzophenones and their use as fungicides GAF CORPORATION (US) 1982-05-11 US disclosed