SCHEMBL4526045

SCHEMBL4526045

C=CC(=O)Oc1ccc(C(=O)c2ccc(N(C)C)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.61
MAPT P10636 3/20 0.61
ALDH1A1 P00352 2/20 0.61
RAB9A P51151 2/20 0.54
NPC1 O15118 2/20 0.54
LMNA P02545 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
TSHR P16473 1/20 0.48
CYP2C19 P33261 1/20 0.48
THRB P10828 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
ELANE P08246 6/20 0.45
MAOB P27338 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
CNR2 P34972 1/20 0.42
TP53 P04637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1263952 0.92 THRB (0.54) HPGDMAPTALDH1A1RAB9ANPC1
SCHEMBL13777536 0.90 ELANE (0.49) HPGDMAPTALDH1A1RAB9ANPC1
SCHEMBL4132764 0.86 THRB (0.55) MAPTRAB9ALMNAMEN1KMT2A
SCHEMBL17834009 0.85 RAB9A (0.53) HPGDMAPTALDH1A1RAB9ANPC1
SCHEMBL4537455 0.83 THRB (0.51) MAPTALDH1A1MEN1KMT2ATSHR
SCHEMBL11556448 0.83 MAPT (0.50) HPGDMAPTALDH1A1RAB9ANPC1
SCHEMBL21657894 0.83 NPC1 (0.53) MAPTALDH1A1RAB9ANPC1MEN1
SCHEMBL12149032 0.83 THRB (0.50) HPGDMAPTALDH1A1RAB9ANPC1
SCHEMBL12149002 0.83 THRB (0.50) HPGDMAPTALDH1A1RAB9ANPC1
SCHEMBL13777546 0.82 LMNA (0.49) HPGDMAPTALDH1A1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090202791-A1 ULTRAVIOLET-CURABLE POLYMER COMPOSITION, RESIN MOLDED ARTICLE AND METHOD FOR PRODUCING SAME JSR CORPORATION (JP) 2009-08-13 US disclosed
EP-1958968-A1 ULTRAVIOLET-CURABLE POLYMER COMPOSITION, RESIN MOLDED ARTICLE AND METHOD FOR PRODUCING SAME JSR Corporation (JP) 2008-08-20 EP disclosed
US-20070084369-A1 Flexographic printing plate and process for production thereof JSR CORPORATION (JP) 2007-04-19 US disclosed
EP-1167025-B1 Polymeric material for laser processing JSR CORP (JP) 2006-11-08 EP disclosed
US-20050277061-A1 Polymeric material for laser processing and a laminated body for laser processing thereof, flexographic printing plate and the method of producing the same, and a seal material JSR CORPORATION (JP) 2005-12-15 US disclosed
US-20020018958-A1 For engraving; odor/fume free; low adhesion of the worked surface for seals JSR CORPORATION (JP) 2002-02-14 US disclosed
EP-1167025-A2 Polymeric material for laser processing JSR Corporation (JP) 2002-01-02 EP disclosed
EP-0343666-B1 Correct-reading images from photopolymer electrographic master DU PONT (US) 1994-08-03 EP disclosed
EP-0084851-B2 PROCESS FOR PREPARING AN OVERCOATED PHOTOPOLYMER PRINTING PLATE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-07-14 EP disclosed
EP-0185337-B1 PROCESS FOR PREPARING PHOTOPOLYMER FLEXOGRAPHIC ELEMENT WITH MELT EXTRUSION COATED ELASTOMERIC SURFACE LAYER E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-03-06 EP disclosed
US-4180403-A PHOTORESISTS, ADDITION POLYMERS, DISSOCIATION OF NITROSO DIMERS TO NITROSO INHIBITORS OF POLYMERIZATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-12-25 US disclosed
US-4177074-A HIGH AND LOW MOLECULAR WEIGHT POLYMERS CONTAINING CARBOXYL GROUPS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-12-04 US disclosed
EP-0005379-A2 Photosensitive compositions containing carbonylic halides as activators Dynachem Corporation (US) 1979-11-14 EP disclosed
EP-0005380-A2 Phototropic photosensitive compositions containing a fluoran colorformer Dynachem Corporation (US) 1979-11-14 EP disclosed
US-4168981-A Bis(substituted amino)sulfides as reversible inhibitor sources for photopolymerization E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-09-25 US disclosed
US-4168982-A Photopolymerizable compositions containing nitroso dimers to selectively inhibit thermal polymerization E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-09-25 US disclosed
US-4065315-A Phototropic dye system and photosensitive compositions containing the same DYNACHEM CORPORATION (US) 1977-12-27 US disclosed
US-4050942-A Nitroso-dimer-containing compositions and photoimaging process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-09-27 US disclosed
US-4050941-A PHOTORESISTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-09-27 US disclosed
US-4029505-A PHOTOPOLYMERIZABLE LAYER OF UNSATURATED COMPOUND, DINITROSO COMPOUND, AND FREE-RADICAL GENERATOR E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-06-14 US disclosed