Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | CPS1 | P31327 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4113759 | 0.92 | MAPT (0.61) | MAPTLMNAKDM4EHTTNPSR1 | |
| SCHEMBL5995248 | 0.87 | MAPT (0.63) | MAPTLMNAKDM4EHTTNPSR1 | |
| SCHEMBL4129937 | 0.86 | MAPT (0.55) | MAPTLMNAKDM4EHTTNPSR1 | |
| SCHEMBL17682929 | 0.85 | CPS1 (0.59) | MAPTLMNAKDM4EHTTALDH1A1 | |
| SCHEMBL4126643 | 0.83 | NPC1 (0.53) | MAPTLMNAKDM4EHTTALDH1A1 | |
| SCHEMBL4841620 | 0.82 | CPS1 (0.52) | MAPTLMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30513999 | 0.82 | CPS1 (0.75) | CPS1RAB9ANPC1 | |
| SCHEMBL20855978 | 0.82 | ALDH1A1 (0.60) | MAPTLMNAKDM4EALDH1A1MEN1 | |
| SCHEMBL12859803 | 0.80 | ALDH1A1 (0.58) | LMNAKDM4EHTTALDH1A1CPS1 | |
| SCHEMBL6987660 | 0.78 | KDM2B (0.58) | MAPTLMNAKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221596-A1 | Substtituted aryl oximes | BAYER CROPSCIENCE AG (DE) | 2009-09-03 | — | — | US | disclosed |
| US-20090221596-A1 | Substtituted aryl oximes | BAYER CROPSCIENCE AG (DE) | 2009-09-03 | — | — | US | disclosed |
| US-20090221596-A1 | Substtituted aryl oximes | BAYER CROPSCIENCE AG (DE) | 2009-09-03 | — | — | US | disclosed |
| CN-101193855-A | Substituted aryl oximes | BAYER CROPSCIENCE AG (DE) | 2008-06-04 | — | — | CN | disclosed |
| EP-1883622-A1 | SUBSTITUTED ARYL OXIMES | Bayer CropScience Aktiengesellschaft (DE) | 2008-02-06 | — | — | EP | disclosed |
| WO-2007090434-A1 | SUBSTITUTED ARYL OXIMES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221596-A1 | Substtituted aryl oximes | CYP1A1, PRDX1, CYP1A2 | MAPT 3870/4885LMNA 2761/4885KDM4E 820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.