Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2406752 | 0.83 | TSHR (0.50) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL12131523 | 0.81 | TSHR (0.48) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL2928416 | 0.80 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL10331160 | 0.79 | TSHR (0.46) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL26921080 | 0.79 | TSHR (0.46) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL63384 | 0.79 | TSHR (0.46) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL19039345 | 0.79 | TSHR (0.46) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL31348327 | 0.79 | TSHR (0.46) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL10608124 | 0.78 | TSHR (0.54) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL10301166 | 0.78 | MEN1 (0.45) | TSHRMEN1KMT2ATHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1386924-B1 | MONOMER, POLYMER, AND OCULAR LENS AND CONTACT LENS EACH OBTAINED THEREFROM | JOHNSON & JOHNSON VISION CARE (US) | 2009-06-10 | — | — | EP | disclosed |
| US-7071274-B2 | Monomer, polymer, and ocular lens and contact lens each obtained therefrom | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2006-07-04 | — | — | US | disclosed |
| US-20040106694-A1 | Monomer, polymer, and ocular lens and contact lens each obtained therefrom | JOHNSON & JOHNSON VISION CARE, INC. | 2004-06-03 | — | — | US | disclosed |
| EP-1386924-A1 | MONOMER, POLYMER, AND OCULAR LENS AND CONTACT LENS EACH OBTAINED THEREFROM | Johnson & Johnson Vision Care, Inc. (US) | 2004-02-04 | — | — | EP | disclosed |