SCHEMBL4135033

SCHEMBL4135033

C=C(C)C(=O)OC(C)CC(=O)CC(C)=O

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 1/20 0.32
KDM6B O15054 1/20 0.32
KDM5C P41229 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
PHF8 Q9UPP1 1/20 0.32
KDM2A Q9Y2K7 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
THRB P10828 1/20 0.32
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9566411 0.80 TSHR (0.47) TSHRALDH1A1KDM4EKDM6BKDM5C
SCHEMBL9566414 0.80 TSHR (0.47) TSHRALDH1A1KDM4EKDM6BKDM5C
SCHEMBL2349785 0.80 TSHR (0.47) TSHRALDH1A1TDP1THRB
SCHEMBL2540758 0.80 TSHR (0.50) TSHRALDH1A1TDP1THRB
SCHEMBL6365126 0.79 TSHR (0.45) TSHRALDH1A1TDP1THRB
SCHEMBL5627412 0.77 TSHR (0.44) TSHRALDH1A1TDP1THRB
SCHEMBL2544205 0.76 TSHR (0.50) TSHRALDH1A1TDP1THRB
SCHEMBL8744854 0.76 TSHR (0.42) TSHRALDH1A1THRB
SCHEMBL18059980 0.76 TSHR (0.42) TSHRALDH1A1THRB
SCHEMBL25430954 0.75 TSHR (0.52) TSHRALDH1A1TDP1THRBMGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090294876-A1 METHOD FOR DEPOSITION OF AN ULTRA-THIN ELECTROPOSITIVE METAL-CONTAINING CAP LAYER INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2009-12-03 US disclosed
US-20090008725-A1 METHOD FOR DEPOSITION OF AN ULTRA-THIN ELECTROPOSITIVE METAL-CONTAINING CAP LAYER INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2009-01-08 US disclosed
US-6540974-B2 Process for making mixed metal oxides AGERE SYSTEMS INC. 2003-04-01 US disclosed
US-20010040785-A1 Thin film deposition of mixed metal oxides HILCO PATENT ACQUISITION 56, LLC 2001-11-15 US disclosed
US-6312565-B1 Thin film deposition of mixed metal oxides AGERE SYSTEMS GUARDIAN CORP. 2001-11-06 US disclosed