Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL29031187 | 0.86 | GPR84 (0.68) | ALDH1A1ALOX15GPR84FFAR1KDM4E | |
| Phthalic Acid SCHEMBL30521576 | 0.86 | GPR84 (0.68) | ALDH1A1ALOX15GPR84FFAR1KDM4E | |
| Phthalic Acid SCHEMBL29014247 | 0.85 | ALDH1A1 (0.56) | ALDH1A1ALOX15POLBKDM4EMEN1 | |
| Phthalic Acid SCHEMBL1308819 | 0.85 | ALDH1A1 (0.56) | ALDH1A1ALOX15POLBKDM4EMEN1 | |
| Phthalic Acid SCHEMBL11211807 | 0.85 | ALDH1A1 (0.56) | ALDH1A1ALOX15POLBKDM4EMEN1 | |
| SCHEMBL28259253 | 0.80 | ALDH1A1 (0.50) | ALDH1A1ALOX15POLBKDM4EMEN1 | |
| Phthalic Acid SCHEMBL1482851 | 0.80 | ALDH1A1 (0.74) | ALDH1A1ALOX15POLBKDM4EMEN1 | |
| Phthalic Acid SCHEMBL9132518 | 0.80 | ALDH1A1 (0.74) | ALDH1A1ALOX15POLBKDM4EMEN1 | |
| SCHEMBL360594 | 0.79 | — | — | |
| SCHEMBL28756 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787155-B2 | DELAY RELEASE FORMULATION OF A NON-STEROIDAL ANTI-INFLAMMATORY DRUG (NSAID) AND A MIXTURE CONTAINING A PROSTAQLANDIN AND ONE OR MORE EXCIPIENTS; FOR THERAPY OF OSTEOARTHRITIS OR RHEUMATOID ARTHRITIS | NORTON HEALTHCARE LTD. (GB) | 2004-09-07 | — | — | US | claimed |
| US-20030086970-A1 | Anti-inflammatory pharmaceutical formulations | NORTON HEALTHCARE LTD. (GB) | 2003-05-08 | — | — | US | claimed |
| EP-1109538-B1 | ANTI-INFLAMMATORY PHARMACEUTICAL FORMULATIONS | NORTON HEALTHCARE LTD (GB) | 2003-05-02 | — | — | EP | claimed |
| US-6537582-B2 | An oral pharmaceutical dosage from including a mixture of a delay release formulation of a non-steroidal anti-inflammatory drug and a mixture containing prostaglandin and one or more excipients | NORTON HEALTHCARE LTD. (GB) | 2003-03-25 | — | — | US | claimed |
| US-6514525-B2 | Sustained release; mixture of non-steroid antiinflammatory drug, prostaglandin and excipient | NORTON HEALTHCARE LTD (GB) | 2003-02-04 | — | — | US | claimed |
| US-20020090395-A1 | ANTI-INFLAMMATORY PHARMACEUTICAL FORMULATIONS | WOOLFE AUSTEN JOHN | 2002-07-11 | — | — | US | claimed |
| EP-1216030-A1 | ANTI-INFLAMMATORY PHARMACEUTICAL FORMULATIONS | NORTON HEALTHCARE LIMITED (GB) | 2002-06-26 | — | — | EP | claimed |
| US-6387410-B1 | MIXTURE CONTAINING NSAID, PROSTAGLANDIN AND ONE OR MORE EXCIPIENTS | NORTON HEALTHCARE LTD (GB) | 2002-05-14 | — | — | US | claimed |
| US-20020054908-A1 | Anti-inflammatory pharmaceutical formulations | WOOLFE AUSTEN JOHN | 2002-05-09 | — | — | US | claimed |
| US-20020015736-A1 | Anti-inflammatory pharmaceutical formulations | NORTON HEALTHCARE LTD. (GB) | 2002-02-07 | — | — | US | claimed |
| EP-1109538-A1 | ANTI-INFLAMMATORY PHARMACEUTICAL FORMULATIONS | NORTON HEALTHCARE LIMITED (GB) | 2001-06-27 | — | — | EP | claimed |
| WO-2001024778-A1 | ANTI-INFLAMMATORY PHARMACEUTICAL FORMULATIONS | NORTON HEALTHCARE LTD. (GB) | 2001-04-12 | — | — | WO | claimed |
| WO-2000015200-A1 | ANTI-INFLAMMATORY PHARMACEUTICAL FORMULATIONS | NORTON HEALTHCARE LTD. (GB) | 2000-03-23 | — | — | WO | claimed |
| US-20090214640-A1 | DELAYED RELEASE PHARMACEUTICAL ORAL DOSAGE FORM AND METHOD OF MAKING SAME | INTELGENX CPORP. | 2009-08-27 | — | — | US | disclosed |
| EP-1988886-A1 | DELAYED RELEASE PHARMACEUTICAL ORAL DOSAGE FORM AND METHOD OF MAKING SAME | Intelgenx Corporation (CA) | 2008-11-12 | — | — | EP | disclosed |
| EP-1855647-A1 | DELAYED RELEASE PHARMACEUTICAL ORAL DOSAGE FORM AND METHOD OF MAKING SAME | Intelgenx Corporation (CA) | 2007-11-21 | — | — | EP | disclosed |
| EP-1091731-A1 | ANTI-INFLAMMATORY PHARMACEUTICAL FORMULATIONS | NORTON HEALTHCARE LIMITED (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2001024778-A1 | ANTI-INFLAMMATORY PHARMACEUTICAL FORMULATIONS | NORTON HEALTHCARE LTD. (GB) | 2001-04-12 | — | — | WO | disclosed |
| WO-2000015200-A1 | ANTI-INFLAMMATORY PHARMACEUTICAL FORMULATIONS | NORTON HEALTHCARE LTD. (GB) | 2000-03-23 | — | — | WO | disclosed |
| WO-2000001368-A1 | ANTI-INFLAMMATORY PHARMACEUTICAL FORMULATIONS | NORTON HEALTHCARE LTD. (GB) | 2000-01-13 | — | — | WO | disclosed |