SCHEMBL4135932

SCHEMBL4135932

CCS(=O)(=O)Oc1ccc(F)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
YAP1 P46937 1/20 0.59
TEAD4 Q15561 1/20 0.59
TEAD2 Q15562 1/20 0.59
MMP2 P08253 2/20 0.47
MMP9 P14780 2/20 0.47
MMP14 P50281 2/20 0.47
MMP7 P09237 1/20 0.47
CA2 P00918 5/20 0.45
CA12 O43570 3/20 0.45
ENPP3 O14638 1/20 0.43
ENPP1 P22413 1/20 0.43
ENPP2 Q13822 1/20 0.43
SOS1 Q07889 1/20 0.42
CA9 Q16790 3/20 0.42
CA1 P00915 2/20 0.42
CA7 P43166 1/20 0.40
KMT2A Q03164 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL576200 0.89 MMP2 (0.55) YAP1TEAD4TEAD2MMP2MMP9
SCHEMBL27540932 0.86 MMP2 (0.51) YAP1TEAD4TEAD2MMP2MMP9
SCHEMBL15763975 0.84 YAP1 (0.45) YAP1TEAD4TEAD2MMP2MMP9
SCHEMBL28588755 0.80 MMP2 (0.52) YAP1TEAD4TEAD2MMP2MMP9
SCHEMBL27676484 0.80 CA2 (0.59) YAP1TEAD4TEAD2MMP2MMP9
SCHEMBL21354197 0.80 MMP2 (0.49) YAP1TEAD4TEAD2MMP2MMP9
SCHEMBL27622145 0.80 CA2 (0.59) MMP2MMP9MMP14MMP7CA2
SCHEMBL28509968 0.78 YAP1 (0.48) YAP1TEAD4TEAD2MMP2MMP9
SCHEMBL4132581 0.78 YAP1 (0.41) YAP1TEAD4TEAD2MMP2MMP9
SCHEMBL9364422 0.78 TDP1 (0.50) YAP1TEAD4TEAD2MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112218852-A Oxidized bis (3-indolyl) methane and uses thereof 桑福德·伯纳姆·普雷比医学发现研究所 2021-01-12 CN claimed
US-12100809-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-24 US disclosed
US-20220149436-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2022-05-12 US disclosed
US-11283107-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2022-03-22 US disclosed
CN-108602776-B Heteroaryl compounds as IRAK inhibitors and uses thereof 默克专利有限公司 2021-12-03 CN disclosed
CN-112218852-A Oxidized bis (3-indolyl) methane and uses thereof 桑福德·伯纳姆·普雷比医学发现研究所 2021-01-12 CN disclosed
EP-3621141-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2020-03-11 EP disclosed
US-20190229372-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2019-07-25 US disclosed
US-10333172-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2019-06-25 US disclosed
US-10290901-B2 2019-05-14 US disclosed
US-20150056503-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2015-02-26 US disclosed
CN-101951771-A Composition for agricultural use for controlling or preventing plant diseases caused by plant pathogens SUMITOMO CHEMICAL CO 2011-01-19 CN disclosed
CN-1854133-B Heterocycle-bearing onium salts WAKO PURE CHEM IND LTD 2010-11-10 CN disclosed
CN-100475803-C Heterocyclic onium salt WAKO PURE CHEM IND LTD (JP) 2009-04-08 CN disclosed
EP-2012386-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY Mitsubishi Chemical Corporation (JP) 2009-01-07 EP disclosed
CN-101263140-A Heterobicyclic compounds as glucokinase activators ASTRAZENECA AB (SE) 2008-09-10 CN disclosed
CN-100381421-C Process for producing triarylsulfonium salt WAKO PURE CHEM IND LTD (JP) 2008-04-16 CN disclosed
CN-1871212-A Process for producing triarylsulfonium salt WAKO PURE CHEM IND LTD (JP) 2006-11-29 CN disclosed
CN-1854133-A Heterocycle-bearing onium salts WAKO PURE CHEM IND LTD (JP) 2006-11-01 CN disclosed
CN-1622943-A Heterocyclic onium salt WAKO PURE CHEM IND LTD (JP) 2005-06-01 CN disclosed